{"id":"W2030123605","doi":"10.1158/1538-7445.am2011-3534","title":"Abstract 3534: PBI-1402, a first-in-class erythropoiesis regulating agent, possesses differentiation properties and demonstrates synergistic anticancer activity in combination with chemotherapy","year":2011,"lang":"en","type":"article","venue":"Cancer Research","topic":"Erythropoietin and Anemia Treatment","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Liminal BioSciences (Canada)","funders":"","keywords":"Gemcitabine; Pharmacology; Cancer research; Erythropoietin; Medicine; Anemia; Chemotherapy; Chemistry; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008025552,0.0004307876,0.0003192617,0.0002691099,0.00008703963,0.0001624677,0.0001749295,0.0002021073,0.003157287],"category_scores_gemma":[0.00006393276,0.00008639503,0.0001670555,0.000184458,0.0001553151,0.000120912,0.0002002033,0.0004311212,0.0005811349],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001939027,"about_ca_system_score_gemma":0.0002350802,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003414812,"about_ca_topic_score_gemma":0.0002970814,"domain_scores_codex":[0.9999462,0.00000873404,0.000003959524,0.000009513798,0.00001818411,0.00001328321],"domain_scores_gemma":[0.9999703,0.000004283525,0.000006747369,0.000002158502,0.000003179866,0.00001320252],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001441902,0.0004292525,0.0005275756,0.0002276185,0.00003495247,0.0001798447,0.00002134382,0.0004529786,0.9704235,0.0003153102,0.0009853011,0.02496046],"study_design_scores_gemma":[0.0003724573,0.005389495,0.004824645,0.00001710274,0.00007500444,0.001429543,0.00001173013,0.00137616,0.9721462,0.00008302868,0.01426496,0.000009570117],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9792778,0.007127502,0.002592571,0.0002690605,0.0001111526,0.0001018832,0.0005645329,0.0002373343,0.009718223],"genre_scores_gemma":[0.9871883,0.002849937,0.002084445,0.00008276238,0.00005064357,0.00006036368,0.001130092,0.00002532421,0.006528199],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003157287,"threshold_uncertainty_score":0.01056218,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1081220465192479,"score_gpt":0.3464588619104462,"score_spread":0.2383368153911984,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}