{"id":"W2030127546","doi":"10.1002/btpr.501","title":"Enzymatic fragmentation of cation exchange membrane bound immunoglobulin G","year":2010,"lang":"en","type":"article","venue":"Biotechnology Progress","topic":"Protein purification and stability","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"","keywords":"Chemistry; Membrane; Fragmentation (computing); Chromatography; Microporous material; Enzyme; Steric effects; Macromolecule; Reaction rate constant; Stereochemistry; Organic chemistry; Kinetics; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002532653,0.0001011408,0.0001147873,0.00006698023,0.00006043606,0.000009977159,0.0002468439,0.0004524136,0.00005603582],"category_scores_gemma":[0.0001156963,0.00009900498,0.00004351888,0.000130052,0.0004201704,0.000004611891,0.00007264048,0.0001398447,0.00001136036],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000007845509,"about_ca_system_score_gemma":0.00004508679,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000122222,"about_ca_topic_score_gemma":0.00003808032,"domain_scores_codex":[0.9992313,0.00003763006,0.0002372017,0.000256304,0.0000920477,0.000145564],"domain_scores_gemma":[0.9991468,0.000005659522,0.0001645159,0.000562361,0.00009303223,0.00002770005],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003639985,0.0001154971,0.002219911,0.00005547639,0.00002066019,3.157914e-7,0.00003861966,2.938041e-7,0.9694741,0.00169588,0.0000401049,0.02630278],"study_design_scores_gemma":[0.0003350942,0.0001292848,0.007326194,0.000005402157,0.00000963231,0.000008842661,0.0000451348,0.00002918843,0.9776728,0.0002257454,0.01411044,0.0001023063],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9957604,0.001634246,0.0007967756,0.001013729,0.0001675343,0.0004125139,0.00001516895,0.00004847589,0.0001511175],"genre_scores_gemma":[0.9955575,0.0001217463,0.003910658,0.00003484994,0.00004189534,0.0001119149,0.0001212912,0.00001021302,0.00008989046],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02620047,"threshold_uncertainty_score":0.4037306,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0070343931608231,"score_gpt":0.2586746231153163,"score_spread":0.2516402299544932,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}