{"id":"W2030180518","doi":"10.1002/mus.20542","title":"Oxidative stress and antioxidant enzyme upregulation in SOD1‐G93A mouse skeletal muscle","year":2006,"lang":"en","type":"article","venue":"Muscle & Nerve","topic":"Amyotrophic Lateral Sclerosis Research","field":"Medicine","cited_by":74,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University; McMaster University Medical Centre","funders":"","keywords":"SOD1; Superoxide dismutase; Oxidative stress; Skeletal muscle; Amyotrophic lateral sclerosis; Endocrinology; Internal medicine; Antioxidant; Malondialdehyde; SOD2; Biology; Downregulation and upregulation; Catalase; Genetically modified mouse; Chemistry; Transgene; Biochemistry; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001777355,0.0005057226,0.0002841902,0.0006681106,0.0002466476,0.0002414275,0.0001731597,0.0003874933,0.001011549],"category_scores_gemma":[0.00008897472,0.0002959534,0.0002941994,0.0002785781,0.0002742828,0.0002293385,0.0002032941,0.0006351486,0.0002771312],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002144522,"about_ca_system_score_gemma":0.00009499431,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005074856,"about_ca_topic_score_gemma":0.0009602243,"domain_scores_codex":[0.9998535,0.00002057937,0.0000190064,0.00004214784,0.0000382227,0.00002655978],"domain_scores_gemma":[0.9998888,0.000007625872,0.00004201367,0.00001250102,0.00001485927,0.0000341776],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001053947,0.00001778202,0.000345961,0.00002002133,0.000006310388,0.0000513674,0.00001830114,0.000008977161,0.9989668,0.00001472228,0.00001252716,0.0004318623],"study_design_scores_gemma":[0.00004035815,0.0007736349,0.04411251,0.00001762122,0.00005604959,0.0006300801,0.00009581044,0.0002352364,0.9529759,0.00008480243,0.00096858,0.000009503433],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9965208,0.00161857,0.0009598853,0.00005293995,0.00001780113,0.00001776929,0.0003377527,0.00006281464,0.0004117455],"genre_scores_gemma":[0.9900556,0.002022976,0.003202259,0.00008058571,0.00001451199,0.00008561125,0.0009012197,0.00003507312,0.003602183],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001011549,"threshold_uncertainty_score":0.003383994,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01775149067027426,"score_gpt":0.2686130757965852,"score_spread":0.2508615851263109,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}