{"id":"W2030287509","doi":"10.1016/j.clinbiochem.2012.06.015","title":"Standardized Procedural Practices of the Ontario Prenatal Screening Program for aneuploidies and open neural tube defects","year":2012,"lang":"en","type":"article","venue":"Clinical Biochemistry","topic":"Prenatal Screening and Diagnostics","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":false,"ca_institutions":"Trillium Health Centre; North York General Hospital; London Health Sciences Centre; McMaster University; University of Toronto; Children's Hospital of Eastern Ontario; University of Ottawa","funders":"","keywords":"Prenatal screening; Trisomy; Standardization; Neural tube; Medicine; Prenatal diagnosis; Modalities; Neural tube defect; Medical physics; Down syndrome; Gynecology; Pediatrics; Pregnancy; Computer science; Psychiatry; Fetus; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004859515,0.0002266441,0.0002277007,0.001973326,0.002494017,0.0009303458,0.001052665,0.0005348445,0.001720414],"category_scores_gemma":[0.01936352,0.0004063879,0.0003803379,0.001955685,0.001026124,0.0002779244,0.0009852641,0.0006269768,0.0002556908],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.02441455,"about_ca_system_score_gemma":0.06484629,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.8588213,"about_ca_topic_score_gemma":0.9380466,"domain_scores_codex":[0.9917937,0.00264563,0.0008968097,0.0007415086,0.003193223,0.0007291887],"domain_scores_gemma":[0.9838035,0.002726558,0.002843393,0.001473041,0.007196475,0.001957097],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0006770123,0.0007487306,0.7672423,0.0004568807,0.0001003535,0.001175531,0.01672561,0.003109312,0.007274286,0.002240294,0.02607512,0.1741746],"study_design_scores_gemma":[0.00003846125,0.0002348894,0.9807807,0.0001443281,0.00002249558,0.0003363849,0.002275998,0.001055003,0.0009257914,0.0001613649,0.01397998,0.00004451777],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9363784,0.001632876,0.0108593,0.006502376,0.0002303498,0.006320879,0.004616727,0.0002667274,0.03319228],"genre_scores_gemma":[0.9524742,0.002182435,0.02780024,0.00166577,0.0001107271,0.002853459,0.002559985,0.0000808301,0.01027232],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.8588213,"threshold_uncertainty_score":0.2840201,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08634432900272401,"score_gpt":0.4183860052206002,"score_spread":0.3320416762178762,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}