{"id":"W2030310377","doi":"10.1371/journal.pone.0003476","title":"Stat1 Phosphorylation Determines Ras Oncogenicity by Regulating p27Kip1","year":2008,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Cytokine Signaling Pathways and Interactions","field":"Medicine","cited_by":33,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Jewish General Hospital","funders":"Canadian Institutes of Health Research; Canadian Breast Cancer Research Alliance","keywords":"STAT1; Phosphorylation; Carcinogenesis; Immunosurveillance; Biology; Cancer research; Tyrosine phosphorylation; Transcription factor; Cell biology; Cancer; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007213619,0.0001143424,0.0002415531,0.00005679201,0.0001685349,0.00001014037,0.00004301274,0.00005766704,0.0005052583],"category_scores_gemma":[0.0001996595,0.0001082545,0.00007476073,0.0001295371,0.00004332013,0.0001082502,0.00002101878,0.0001624591,0.00008047043],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001133762,"about_ca_system_score_gemma":0.00008655038,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001118353,"about_ca_topic_score_gemma":0.000008935493,"domain_scores_codex":[0.9990326,0.00001958652,0.0002641769,0.0002003789,0.0003070775,0.0001761347],"domain_scores_gemma":[0.9993624,0.00007031183,0.00009985275,0.0002096716,0.0001561624,0.0001015916],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009424971,0.0009251282,0.02170936,0.00004258196,0.0001212036,0.00001473555,0.0004431332,0.000004011769,0.9729689,0.000009576442,0.00281833,0.0008487951],"study_design_scores_gemma":[0.0008545387,0.000301272,0.008731039,0.0002404693,0.0001647707,0.00005444907,0.0000420424,0.00295823,0.9848308,0.00002913909,0.00165018,0.0001431002],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9962034,0.0002146981,0.0002468716,0.0003712852,0.00004683511,0.0002248724,0.00002420114,0.0001211439,0.0025467],"genre_scores_gemma":[0.9928009,0.00005601324,0.003271586,0.0002595099,0.0002537796,0.00001832337,0.00008895281,0.00002477878,0.003226161],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01297832,"threshold_uncertainty_score":0.5532224,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07934095601781699,"score_gpt":0.2634621558213696,"score_spread":0.1841211998035526,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}