{"id":"W2030334551","doi":"10.1016/j.bbagen.2015.02.018","title":"Pin1: Intimate involvement with the regulatory protein kinase networks in the global phosphorylation landscape","year":2015,"lang":"en","type":"review","venue":"Biochimica et Biophysica Acta (BBA) - General Subjects","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":false,"ca_institutions":"Western University","funders":"Cancer Research Society","keywords":"Kinome; PIN1; Kinase; Phosphorylation; Biology; Protein phosphorylation; Autophagy-related protein 13; Cell biology; Protein kinase A; Computational biology; Biochemistry; Isomerase; Enzyme","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004141195,0.001091995,0.001156893,0.00138441,0.0002956255,0.001530304,0.0009497061,0.0009873323,0.002132905],"category_scores_gemma":[0.0003627661,0.0003817535,0.0003027421,0.00180476,0.0007714065,0.001641533,0.001171817,0.001901501,0.00145846],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000806011,"about_ca_system_score_gemma":0.0007666514,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005807888,"about_ca_topic_score_gemma":0.001012972,"domain_scores_codex":[0.9998765,0.00001218353,0.00001297774,0.00003788543,0.00003758834,0.00002291969],"domain_scores_gemma":[0.9998794,0.00004285246,0.00002749269,0.000005438496,0.0000250116,0.00001975202],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001730401,0.00004030953,0.0003860037,0.0129062,0.0001266106,0.0004845401,0.00008823878,0.0007922915,0.01108257,0.01555552,0.0239192,0.9344455],"study_design_scores_gemma":[0.00001700835,0.00005162225,0.001380971,0.001083979,0.0001354944,0.001557443,0.00007056268,0.0002070654,0.003731319,0.005689363,0.9860407,0.00003461605],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0003313885,0.9970617,0.0004334922,0.0003322606,0.0002168303,0.000005030228,0.00003583487,0.00001389647,0.001569669],"genre_scores_gemma":[0.002252488,0.9963308,0.0002700168,0.000141202,0.0001916854,0.000007068017,0.0000589009,0.000002021339,0.0007457828],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002132905,"threshold_uncertainty_score":0.007135212,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02298085083774385,"score_gpt":0.2829950764359822,"score_spread":0.2600142255982383,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}