{"id":"W2030383675","doi":"10.1039/b914942m","title":"3′,5′-Cyclic diguanylic acid: a small nucleotide that makes big impacts","year":2010,"lang":"en","type":"review","venue":"Chemical Society Reviews","topic":"Bacterial biofilms and quorum sensing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":44,"is_retracted":false,"has_abstract":true,"ca_institutions":"National Research Council Canada; Institute for Biological Sciences; Brock University","funders":"National Research Council Canada; Natural Sciences and Engineering Research Council of Canada; Directorate for Biological Sciences; Royal Society of Chemistry; Royal Society","keywords":"Biofilm; Riboswitch; Nucleotide; Chemistry; Biochemistry; Synthetic biology; Computational biology; Bacteria; Cell biology; Biology; Genetics; Gene; RNA","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001619057,0.0007433348,0.000744777,0.0007312601,0.0002546318,0.0005003872,0.0005470312,0.0008280914,0.003506168],"category_scores_gemma":[0.0001739223,0.0002501011,0.000218629,0.000985059,0.0002492763,0.0006336237,0.0003935611,0.0008078422,0.004697993],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005205478,"about_ca_system_score_gemma":0.0005319823,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006953815,"about_ca_topic_score_gemma":0.00113151,"domain_scores_codex":[0.9999214,0.000007611306,0.000005095857,0.00001834054,0.00003691272,0.00001049478],"domain_scores_gemma":[0.9999503,0.00001463867,0.000007988183,0.000002264171,0.00001342771,0.00001131219],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00006920747,0.00006985531,0.0001261856,0.00814545,0.00003867679,0.0003027142,0.00007979287,0.0005465414,0.07361519,0.008917016,0.02298806,0.8851013],"study_design_scores_gemma":[0.000007451581,0.00006978054,0.0002542648,0.0003389698,0.00001717874,0.0005127338,0.00002695778,0.00009982303,0.01034545,0.0009452132,0.9873707,0.00001149293],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001571572,0.9859595,0.001375463,0.0003466156,0.0006870058,0.00001711195,0.00005815934,0.00004785599,0.009936607],"genre_scores_gemma":[0.007629141,0.9766494,0.001844865,0.0002803277,0.0002261219,0.0000333225,0.0001480879,0.00001037345,0.01317838],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003506168,"threshold_uncertainty_score":0.01172924,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06042658423044429,"score_gpt":0.3006902261694656,"score_spread":0.2402636419390213,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}