{"id":"W2030396326","doi":"10.1007/s12013-009-9067-2","title":"Mechanotransduction by TRP Channels: General Concepts and Specific Role in the Vasculature","year":2009,"lang":"en","type":"review","venue":"Cell Biochemistry and Biophysics","topic":"Ion Channels and Receptors","field":"Neuroscience","cited_by":169,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; St. Michael's Hospital","funders":"Canadian Institutes of Health Research; Deutsche Forschungsgemeinschaft","keywords":"Transient receptor potential channel; Mechanotransduction; TRPV; TRPC3; TRPV4; TRPM7; TRPC1; Stretch-activated ion channel; Cell biology; TRPC; Biology; Mechanosensation; Ion channel; PIEZO1; TRPC6; Neuroscience; Anatomy; Mechanosensitive channels; Genetics; TRPV1; Receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001049215,0.0004029472,0.0005532432,0.00002805419,0.0001555674,0.0001233011,0.0002591521,0.0004473329,0.000009115426],"category_scores_gemma":[0.000006050127,0.0002561666,0.0001922011,0.0003219015,0.0001873995,0.00005972505,0.00003528079,0.0005180397,0.00000497286],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002100409,"about_ca_system_score_gemma":0.00002791373,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000002357286,"about_ca_topic_score_gemma":4.582585e-8,"domain_scores_codex":[0.998505,0.0001081335,0.0002532956,0.0006685604,0.0001914042,0.0002736103],"domain_scores_gemma":[0.9995188,0.0000521167,0.0001415274,0.0002040079,0.00001278648,0.00007072816],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000007193472,0.000176018,2.872122e-8,0.0033176,0.000008034854,0.00001217039,0.0003709099,0.000001151635,0.4822039,0.00008916135,0.002140059,0.5116737],"study_design_scores_gemma":[0.0001380462,0.00003058667,2.734734e-8,0.0004732182,0.00004999046,0.00003438348,0.00006647856,0.00001060819,0.4300725,0.000149113,0.5686741,0.0003009519],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.007983427,0.9907532,0.000005310371,0.0000616542,0.0003559439,0.0003378394,0.00008501387,0.00002162139,0.0003960127],"genre_scores_gemma":[0.01347601,0.9846159,0.00001051584,0.00009508261,0.000914041,0.00002092379,0.0001206378,0.00002076484,0.0007261466],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.566534,"threshold_uncertainty_score":0.999989,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02189567315115825,"score_gpt":0.2660010204498492,"score_spread":0.244105347298691,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}