{"id":"W2030396326","doi":"10.1007/s12013-009-9067-2","title":"Mechanotransduction by TRP Channels: General Concepts and Specific Role in the Vasculature","year":2009,"lang":"en","type":"review","venue":"Cell Biochemistry and Biophysics","topic":"Ion Channels and Receptors","field":"Neuroscience","cited_by":169,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; St. Michael's Hospital","funders":"Canadian Institutes of Health Research; Deutsche Forschungsgemeinschaft","keywords":"Transient receptor potential channel; Mechanotransduction; TRPV; TRPC3; TRPV4; TRPM7; TRPC1; Stretch-activated ion channel; Cell biology; TRPC; Biology; Mechanosensation; Ion channel; PIEZO1; TRPC6; Neuroscience; Anatomy; Mechanosensitive channels; Genetics; TRPV1; Receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000662465,0.001138844,0.001596423,0.001776456,0.0003212763,0.001168066,0.001292596,0.001344077,0.001563789],"category_scores_gemma":[0.0005670365,0.0003683496,0.0005393508,0.002370113,0.001207373,0.003100413,0.0008700204,0.002644388,0.001596405],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007146199,"about_ca_system_score_gemma":0.0008800845,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005324876,"about_ca_topic_score_gemma":0.0008095476,"domain_scores_codex":[0.9998558,0.00001785459,0.00002292768,0.00004513102,0.00004204905,0.00001629087],"domain_scores_gemma":[0.9997466,0.0001225381,0.00003342401,0.000009962482,0.00005940114,0.00002816625],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001296903,0.00008816001,0.0002017377,0.01209769,0.0000898617,0.0005741474,0.00009734713,0.0009533248,0.00987739,0.01282675,0.02535225,0.9377117],"study_design_scores_gemma":[0.00003149567,0.0001098873,0.001103265,0.001703231,0.00009992506,0.003218458,0.0001251047,0.0003087993,0.002053421,0.01279487,0.9784006,0.00005102442],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.000221935,0.9973562,0.0008355157,0.0003161988,0.0003212646,0.000005016577,0.00001767547,0.00001217093,0.0009140656],"genre_scores_gemma":[0.0007882962,0.9977,0.0004753388,0.0002021033,0.0003201994,0.000007123065,0.00002397153,0.000001681705,0.0004812879],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001776456,"threshold_uncertainty_score":0.00523138,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02189567315115825,"score_gpt":0.2660010204498492,"score_spread":0.244105347298691,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}