{"id":"W2030456669","doi":"10.1016/j.thromres.2007.12.003","title":"Treatment of endothelium with the chemotherapy agent vincristine affects activated protein C generation to a greater degree in newborn plasma than in adult plasma","year":2008,"lang":"en","type":"article","venue":"Thrombosis Research","topic":"Blood Coagulation and Thrombosis Mechanisms","field":"Medicine","cited_by":11,"is_retracted":false,"has_abstract":false,"ca_institutions":"McMaster University; Juravinski Hospital","funders":"","keywords":"Protein C; Vincristine; Heparin; Thrombomodulin; Flow cytometry; Chemistry; Chemotherapy; Medicine; Molecular biology; Internal medicine; Immunology; Biology; Endocrinology; Thrombin; Cyclophosphamide; Platelet","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003994167,0.0002576697,0.000530862,0.0005551273,0.0001397459,0.00002082263,0.0001660688,0.0001291052,0.0001450125],"category_scores_gemma":[0.00006887652,0.0001569807,0.00006818101,0.001187303,0.0001521995,0.0000769289,0.00004296431,0.0002578948,0.00004013511],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004128368,"about_ca_system_score_gemma":0.0002307767,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001507598,"about_ca_topic_score_gemma":0.00222816,"domain_scores_codex":[0.9974055,0.0004006223,0.0003099743,0.0004615583,0.0008799739,0.0005423519],"domain_scores_gemma":[0.9988364,0.0001121157,0.00007457962,0.0005437046,0.0002674427,0.0001657765],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001384268,0.001210517,0.01383398,0.00004432313,0.0001172995,0.00005282505,0.00551938,0.00004619961,0.9722121,0.0001846847,0.0001163423,0.005278112],"study_design_scores_gemma":[0.006094759,0.003473856,0.2087868,0.0001657461,0.00001459155,0.00002239295,0.0002778495,0.001279858,0.7795429,0.000007717953,0.0002060126,0.0001274913],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9901119,0.00001262016,0.00006574907,0.005691292,0.00002346036,0.00319983,0.000008234863,0.00003509265,0.0008517663],"genre_scores_gemma":[0.9969324,0.00009438668,0.001593918,0.0001036472,0.00009242682,0.0005058944,0.00002136046,0.00005311886,0.0006028726],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1949528,"threshold_uncertainty_score":0.6401488,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1503354590653016,"score_gpt":0.3537768948940559,"score_spread":0.2034414358287543,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}