{"id":"W2030485536","doi":"10.1371/journal.ppat.1001252","title":"Induction of a Peptide with Activity against a Broad Spectrum of Pathogens in the Aedes aegypti Salivary Gland, following Infection with Dengue Virus","year":2011,"lang":"en","type":"article","venue":"PLoS Pathogens","topic":"Invertebrate Immune Response Mechanisms","field":"Immunology and Microbiology","cited_by":176,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"Centre National de la Recherche Scientifique; Agence Nationale de la Recherche","keywords":"Aedes aegypti; Biology; Cecropin; Dengue virus; Virology; Dengue fever; Chikungunya; Immune system; Virus; Microbiology; Innate immune system; Antimicrobial peptides; Vector (molecular biology); Salivary gland; Aedes; Gene; Immunology; Genetics; Antimicrobial","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000129307,0.0003408767,0.0002027117,0.0001865652,0.00009792341,0.0002506096,0.00007855983,0.0001689565,0.000641565],"category_scores_gemma":[0.0001174184,0.0001112038,0.0003068595,0.0001133607,0.0001650418,0.0001620407,0.0001726471,0.0003965077,0.0001870923],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000160859,"about_ca_system_score_gemma":0.000150251,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002462439,"about_ca_topic_score_gemma":0.0003563922,"domain_scores_codex":[0.99993,0.00000967926,0.000007158559,0.00001925437,0.00001710607,0.00001675202],"domain_scores_gemma":[0.9998953,0.0000207513,0.00003604009,0.000007399549,0.00001418859,0.00002628299],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002682924,0.000004302076,0.000127785,0.00001689647,0.000001405449,0.00001536713,0.000005344797,0.000007627376,0.9995511,0.000007072236,0.000003918879,0.0002322931],"study_design_scores_gemma":[0.0000162099,0.0005890068,0.04718243,0.00001035816,0.00002340679,0.000411315,0.00007941626,0.0003044115,0.9501331,0.00003170127,0.001213093,0.000005574216],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9973155,0.0008999027,0.0006616292,0.00004187519,0.00001469747,0.00002836196,0.0005083502,0.00001372215,0.0005159653],"genre_scores_gemma":[0.9946175,0.0006890719,0.001850574,0.0000862084,0.00001533682,0.00003828496,0.001313181,0.000009968122,0.001379835],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000641565,"threshold_uncertainty_score":0.002146184,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02610140195295757,"score_gpt":0.2128143144541335,"score_spread":0.1867129125011759,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}