{"id":"W2030485536","doi":"10.1371/journal.ppat.1001252","title":"Induction of a Peptide with Activity against a Broad Spectrum of Pathogens in the Aedes aegypti Salivary Gland, following Infection with Dengue Virus","year":2011,"lang":"en","type":"article","venue":"PLoS Pathogens","topic":"Invertebrate Immune Response Mechanisms","field":"Immunology and Microbiology","cited_by":176,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"Centre National de la Recherche Scientifique; Agence Nationale de la Recherche","keywords":"Aedes aegypti; Biology; Cecropin; Dengue virus; Virology; Dengue fever; Chikungunya; Immune system; Virus; Microbiology; Innate immune system; Antimicrobial peptides; Vector (molecular biology); Salivary gland; Aedes; Gene; Immunology; Genetics; Antimicrobial","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005986193,0.0002719325,0.0004676632,0.0002933839,0.0001326658,0.000007257917,0.0002049498,0.0002447288,0.00005807052],"category_scores_gemma":[0.00006608313,0.0001796602,0.0001387408,0.000488412,0.0001772654,0.0001761518,0.00005549903,0.000408038,0.00002801454],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006216632,"about_ca_system_score_gemma":0.0001230786,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001232552,"about_ca_topic_score_gemma":0.001904994,"domain_scores_codex":[0.9979576,0.0008768977,0.0003400335,0.0003293875,0.0001142029,0.0003818073],"domain_scores_gemma":[0.9989884,0.0001154625,0.0003245148,0.0004874161,0.00006615475,0.000018009],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001131819,0.0007109421,0.03663535,0.00004374992,0.0003564567,0.00006959635,0.004539753,0.00000981768,0.95551,0.0001462387,0.000005492187,0.000840771],"study_design_scores_gemma":[0.001412827,0.0009395533,0.1233174,0.000180333,0.0002097157,0.0001565948,0.0008607417,0.00001513405,0.8725732,0.00008696476,0.00002552826,0.0002219828],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9979738,0.0001727929,0.0004683186,0.00001991349,0.0001488705,0.000558516,0.00005424362,0.00004511878,0.0005584268],"genre_scores_gemma":[0.9993196,0.0000617076,0.0003869206,0.00003575678,0.00001549678,0.0000674353,0.00003326272,0.00003588769,0.00004397883],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.08668209,"threshold_uncertainty_score":0.7326331,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02610140195295757,"score_gpt":0.2128143144541335,"score_spread":0.1867129125011759,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}