{"id":"W2030487055","doi":"10.1371/journal.pone.0112170","title":"FRET-FLIM Investigation of PSD95-NMDA Receptor Interaction in Dendritic Spines; Control by Calpain, CaMKII and Src Family Kinase","year":2014,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Neuroscience and Neuropharmacology Research","field":"Neuroscience","cited_by":33,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institut Universitaire en Santé Mentale de Québec; Université Laval","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"NMDA receptor; Dendritic spine; Förster resonance energy transfer; Calpain; Synaptic plasticity; Cell biology; Biology; Src family kinase; Hippocampal formation; Neuroscience; Kinase; Receptor; Proto-oncogene tyrosine-protein kinase Src; Biochemistry; Enzyme","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004361427,0.0003568327,0.0006481879,0.000248614,0.0003646864,0.0003204162,0.0007760038,0.0005066726,0.001138425],"category_scores_gemma":[0.0002427412,0.0001758673,0.0003089265,0.0003316016,0.0003915885,0.0006091627,0.0004096516,0.001033645,0.0002606127],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006276363,"about_ca_system_score_gemma":0.000206,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008036186,"about_ca_topic_score_gemma":0.0008126441,"domain_scores_codex":[0.9997813,0.00002308534,0.00001467136,0.00006145438,0.00006534589,0.00005423211],"domain_scores_gemma":[0.9999017,0.00002672283,0.00002464364,0.00001287401,0.00001474611,0.00001926676],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005746085,0.00002220646,0.0001106397,0.00004782075,0.000005018097,0.00005777802,0.00003862053,0.00005551744,0.9983473,0.000249412,0.0000288532,0.0009793598],"study_design_scores_gemma":[0.00001638905,0.00006417523,0.002197944,0.000005125928,0.000009810235,0.000252291,0.00004194369,0.002357845,0.9943106,0.0001118512,0.0006258136,0.00000611814],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9798576,0.001710863,0.01549331,0.0001396646,0.00003089781,0.00003837342,0.0003112169,0.00009800238,0.002319988],"genre_scores_gemma":[0.9861703,0.001061609,0.01045946,0.00004924898,0.00001358724,0.00009445741,0.0002830755,0.0000396993,0.00182853],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001138425,"threshold_uncertainty_score":0.004553854,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06698709381003581,"score_gpt":0.2925913553749639,"score_spread":0.2256042615649281,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}