{"id":"W2030543450","doi":"10.1007/s10522-014-9534-z","title":"Age-dependent metabolic dysregulation in cancer and Alzheimer’s disease","year":2014,"lang":"en","type":"review","venue":"Biogerontology","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":97,"is_retracted":false,"has_abstract":false,"ca_institutions":"Western University","funders":"","keywords":"Neurodegeneration; Anaerobic glycolysis; Glycolysis; Biology; Disease; Cancer; Neuroscience; Cognitive decline; Bioinformatics; Medicine; Internal medicine; Endocrinology; Metabolism; Dementia; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000547484,0.0007912687,0.001331544,0.001340862,0.0002393381,0.0009509243,0.000893403,0.001088205,0.00278019],"category_scores_gemma":[0.0005226459,0.0002282848,0.0003282405,0.001782914,0.0005167589,0.001134789,0.0007615405,0.001296394,0.001217312],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000608338,"about_ca_system_score_gemma":0.001022481,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001379515,"about_ca_topic_score_gemma":0.003109771,"domain_scores_codex":[0.9998889,0.00001689336,0.00001689341,0.0000230751,0.00003969999,0.0000144642],"domain_scores_gemma":[0.9998353,0.00005457649,0.00003300176,0.000005873622,0.00005025219,0.00002091336],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001063419,0.00005270304,0.0002961911,0.01124052,0.0001017168,0.0002765023,0.00004777,0.0003612112,0.001694948,0.003410981,0.02768526,0.9547257],"study_design_scores_gemma":[0.00002821478,0.00008550853,0.001700657,0.002759223,0.000191441,0.001635251,0.00009360972,0.0001215274,0.0005688429,0.003998607,0.9887913,0.00002584429],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00009933427,0.9990584,0.00009913743,0.0001982963,0.0001279093,0.000002059267,0.00001545256,0.000004378609,0.0003950663],"genre_scores_gemma":[0.0007299056,0.9984685,0.000116049,0.0001078579,0.0001715157,0.000003016165,0.00002315153,7.140938e-7,0.000379352],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.00278019,"threshold_uncertainty_score":0.009300709,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05930482678297139,"score_gpt":0.3486580715517098,"score_spread":0.2893532447687384,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}