{"id":"W2030587074","doi":"10.1016/j.cellsig.2008.04.014","title":"Wnt and beyond Wnt: Multiple mechanisms control the transcriptional property of β-catenin","year":2008,"lang":"en","type":"article","venue":"Cellular Signalling","topic":"FOXO transcription factor regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":213,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Wnt signaling pathway; Cell biology; Biology; Transcription factor; Beta-catenin; PI3K/AKT/mTOR pathway; Signal transduction; Chemistry; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001855465,0.0001344196,0.0001358582,0.00002929984,0.0001571029,0.00001048343,0.0001222981,0.0001091998,0.0000291026],"category_scores_gemma":[0.00001672362,0.00008778828,0.00009883475,0.00005036578,0.0001582095,0.000007027248,0.00001200755,0.00008169357,0.000003246935],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000006861317,"about_ca_system_score_gemma":0.0000363134,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000131767,"about_ca_topic_score_gemma":0.000006370768,"domain_scores_codex":[0.9991137,0.00007115187,0.0002326046,0.0002448304,0.0001819023,0.0001557427],"domain_scores_gemma":[0.9996369,0.00001617102,0.0000738224,0.0001265061,0.00009391573,0.00005270288],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009731272,0.0000385528,0.0003727004,0.00001647909,0.00004884565,0.000002117446,0.0001881635,0.0009986567,0.9973653,0.0006612297,0.00002013243,0.0001905],"study_design_scores_gemma":[0.001067135,0.0001426895,0.001257923,0.000009537496,0.00003322441,0.00001924512,0.0000596944,0.004108386,0.9912846,0.0003035969,0.001571179,0.0001427688],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8037506,0.001561393,0.1940564,0.0001517228,0.00008684674,0.0002792182,0.00001772237,0.00001151954,0.0000845483],"genre_scores_gemma":[0.9983714,0.00008078653,0.0008767678,0.00010803,0.00007164516,0.00001821259,0.00009120899,0.00001978761,0.0003622125],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1946207,"threshold_uncertainty_score":0.3579902,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01489538113655847,"score_gpt":0.1847829816692143,"score_spread":0.1698876005326558,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}