{"id":"W2030604662","doi":"10.1089/hgtb.2012.122","title":"Efficacy and Site-Specificity of Adenoviral Vector Integration Mediated by the Phage φC31 Integrase","year":2012,"lang":"en","type":"article","venue":"Human Gene Therapy Methods","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre hospitalier de l'Université Laval; Université Laval; Montreal Neurological Institute and Hospital; Université de Montréal; Biotechnology Research Institute","funders":"Canadian Institutes of Health Research","keywords":"Biology; Molecular biology; Expression cassette; Puromycin; C2C12; Integrase; HeLa; Gene; Virology; Genetic enhancement; Viral vector; Vector (molecular biology); Genetics; Cell culture; Recombinant DNA; Myogenesis","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002245686,0.000250113,0.0002529788,0.00007060383,0.000175023,0.00003002067,0.0003294273,0.0001726284,0.0001980258],"category_scores_gemma":[0.0001397075,0.0001720955,0.0001015481,0.0001801698,0.0003147679,0.00001087382,0.00008822657,0.0002412097,0.000006535929],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001804552,"about_ca_system_score_gemma":0.00003720705,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003447792,"about_ca_topic_score_gemma":0.00002967239,"domain_scores_codex":[0.9973646,0.001386281,0.0003214327,0.0003210667,0.0002235631,0.0003830738],"domain_scores_gemma":[0.9988586,0.0001663583,0.0001445966,0.0005894867,0.0001053808,0.0001355642],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001613069,0.0001960055,0.0002403698,0.000004603942,0.000105078,3.225462e-7,0.0006689693,0.000001580053,0.9521599,0.00005220041,0.0007474155,0.0442105],"study_design_scores_gemma":[0.00136203,0.001889197,0.001968894,0.000004873888,0.00001615996,0.000005996621,0.0001014434,0.00002461874,0.9874348,0.00004071189,0.006964604,0.0001866764],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9766942,0.01584067,0.006589974,0.00009299155,0.0000996925,0.0004342879,0.00004527544,0.00001962019,0.0001833026],"genre_scores_gemma":[0.9935204,0.001316298,0.003910986,0.0002326719,0.0003581248,0.00004556678,0.0002732389,0.00005080702,0.0002918741],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04402382,"threshold_uncertainty_score":0.7017849,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06258507270615138,"score_gpt":0.3977963237113091,"score_spread":0.3352112510051577,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}