{"id":"W2030617384","doi":"10.1039/c4cp05003g","title":"Why ice-binding type I antifreeze protein acts as a gas hydrate crystal inhibitor","year":2015,"lang":"en","type":"article","venue":"Physical Chemistry Chemical Physics","topic":"Freezing and Crystallization Processes","field":"Engineering","cited_by":101,"is_retracted":false,"has_abstract":true,"ca_institutions":"National Research Council Canada; University of British Columbia","funders":"University of British Columbia; Western Canada Research Grid; Compute Canada","keywords":"Antifreeze protein; Hydrate; Chemistry; Methane; Clathrate hydrate; Ice crystals; Antifreeze; Molecule; Molecular dynamics; Stereochemistry; Crystallography; Organic chemistry; Biochemistry; Computational chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00004984947,0.00037135,0.0003400075,0.0000120355,0.00005159186,0.0001066842,0.0003101968,0.0001461069,0.00002805735],"category_scores_gemma":[0.0001745282,0.0003860917,0.0001080126,0.0005085089,0.0001195246,0.0003062025,0.0001034377,0.0004351865,0.0001403991],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001433217,"about_ca_system_score_gemma":0.00008922285,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000005700589,"about_ca_topic_score_gemma":1.441172e-7,"domain_scores_codex":[0.9984266,0.00001010336,0.0002411971,0.0003864237,0.0004611551,0.0004745668],"domain_scores_gemma":[0.9989495,0.00004057478,0.0000666924,0.0003405673,0.0002062873,0.0003963542],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002950933,0.0001779202,0.000003788484,0.0003806457,0.0000384821,0.000007313901,0.0001890128,0.00190076,0.9895825,0.0001424911,0.007362873,0.0001846788],"study_design_scores_gemma":[0.0004585749,0.00002492465,1.457657e-7,0.0001103724,0.00002761029,0.000005431572,0.00005498198,0.01202487,0.9716265,0.007498804,0.007704562,0.0004632792],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9765327,0.0000714891,0.0006350195,0.00009137719,0.00007447928,0.0001367617,0.00001668782,0.0007384287,0.02170307],"genre_scores_gemma":[0.9977366,0.000003683713,0.000152366,0.00007053094,0.001445568,0.00003256904,0.0001504953,0.0000958074,0.0003123888],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02139068,"threshold_uncertainty_score":0.9998591,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01563199064685258,"score_gpt":0.2222814756852296,"score_spread":0.206649485038377,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}