{"id":"W2030646983","doi":"10.1038/sj.bjc.6605727","title":"Metronomic gemcitabine suppresses tumour growth, improves perfusion, and reduces hypoxia in human pancreatic ductal adenocarcinoma","year":2010,"lang":"en","type":"article","venue":"British Journal of Cancer","topic":"Cancer, Hypoxia, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":87,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; BC Cancer Agency","funders":"Canadian Cancer Society Research Institute; Terry Fox Foundation; Michael Smith Health Research BC","keywords":"Gemcitabine; Pancreatic cancer; Medicine; Hypoxia (environmental); Oncology; Internal medicine; Pancreatic ductal adenocarcinoma; Cancer; Apoptosis; Cancer research; Biology; Chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007174304,0.0001348518,0.0002175328,0.0001077625,0.00008968036,0.0001592992,0.0000919867,0.0001355483,0.0005713685],"category_scores_gemma":[0.0001158872,0.00009122428,0.0000911688,0.0001357137,0.0000933622,0.0001005342,0.0000964832,0.0002508857,0.00009719805],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001921839,"about_ca_system_score_gemma":0.0001069413,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003260091,"about_ca_topic_score_gemma":0.0007271306,"domain_scores_codex":[0.9999429,0.00001430473,0.000006847609,0.000007735832,0.00001591461,0.00001231199],"domain_scores_gemma":[0.999964,0.000007624184,0.00001091997,0.000005330148,0.000003346198,0.000008712574],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0009835042,0.0001295699,0.001028289,0.0000659619,0.00001287788,0.00004777784,0.00001997105,0.0002482818,0.9903852,0.00003414206,0.00009687611,0.006947658],"study_design_scores_gemma":[0.0001990721,0.007624859,0.04283677,0.000009004706,0.00005940733,0.001038015,0.00006529784,0.001458573,0.9429922,0.00006007149,0.003648147,0.000008615243],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9985903,0.000802661,0.0002210149,0.00003003425,0.000006898963,0.000007706441,0.00006101418,0.00001773925,0.0002625959],"genre_scores_gemma":[0.9988515,0.0004141048,0.0002585445,0.00001508164,0.000002933713,0.00001134427,0.0001324752,0.000005311969,0.0003086509],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005713685,"threshold_uncertainty_score":0.001911402,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004677069748060372,"score_gpt":0.2360526396263442,"score_spread":0.2313755698782838,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}