{"id":"W2030653144","doi":"10.4161/cc.23722","title":"Cigarette smoke metabolically promotes cancer, via autophagy and premature aging in the host stromal microenvironment","year":2013,"lang":"en","type":"article","venue":"Cell Cycle","topic":"Cancer, Hypoxia, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":58,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Cancer Research","funders":"National Institute on Aging","keywords":"Autophagy; Biology; Tumor microenvironment; Cancer research; Mitophagy; Stromal cell; Cancer; Angiogenesis; Cell biology; Apoptosis; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001056424,0.000183996,0.0001333895,0.000157019,0.0001273704,0.0001893419,0.00007124671,0.0002029649,0.0005803359],"category_scores_gemma":[0.00004644458,0.00006692648,0.0002643732,0.00009739696,0.000111682,0.0001008293,0.0001461658,0.0002331923,0.00009320857],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001487746,"about_ca_system_score_gemma":0.0001949683,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004275917,"about_ca_topic_score_gemma":0.001042677,"domain_scores_codex":[0.9999493,0.0000111381,0.000005140838,0.000009732477,0.00001388535,0.00001089323],"domain_scores_gemma":[0.9999632,0.000004392751,0.00001167685,0.000005618007,0.000006703079,0.000008475507],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003159596,0.0000533254,0.004467573,0.0001007988,0.00002444726,0.0003044959,0.00003177386,0.00006457822,0.988629,0.0004480582,0.00008381778,0.005476214],"study_design_scores_gemma":[0.00002780667,0.0008759224,0.1017581,0.00003300171,0.000131042,0.002059406,0.0001037814,0.001426519,0.8858206,0.0005623343,0.007189719,0.00001188531],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9816962,0.01389625,0.002152089,0.0002616852,0.00005685187,0.00002125798,0.0001522945,0.00005678149,0.001706537],"genre_scores_gemma":[0.99251,0.005154844,0.0006801906,0.00009102953,0.00002195966,0.00001350607,0.0001007891,0.000004942584,0.001422657],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005803359,"threshold_uncertainty_score":0.001941442,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004836103821172525,"score_gpt":0.2115598135656058,"score_spread":0.2067237097444333,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}