{"id":"W2030682910","doi":"10.1097/00000542-200103000-00020","title":"Blockade of AMPA Receptors and Volatile Anesthetics","year":2001,"lang":"en","type":"article","venue":"Anesthesiology","topic":"Neuroscience and Neuropharmacology Research","field":"Neuroscience","cited_by":42,"is_retracted":false,"has_abstract":true,"ca_institutions":"Health Sciences Centre; Hospital for Sick Children; University of Toronto; Sunnybrook Health Science Centre","funders":"Medical Research Council; National Institute of General Medical Sciences; U.S. Public Health Service","keywords":"AMPA receptor; Halothane; Isoflurane; Receptor; Glutamate receptor; GABAA receptor; Pharmacology; Anesthetic; Convulsant; Minimum alveolar concentration; Excitatory postsynaptic potential; Medicine; Kainate receptor; Blockade; Neuroscience; Anesthesia; Internal medicine; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001700322,0.0001220066,0.0002199758,0.0001469674,0.0001286777,0.000009721325,0.0003129035,0.00008867148,0.0001709872],"category_scores_gemma":[0.000318933,0.0001025233,0.00003601085,0.0003770128,0.0009393769,0.00008583932,0.00008757567,0.0001962295,0.0000588155],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000005132146,"about_ca_system_score_gemma":0.00003899228,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001207213,"about_ca_topic_score_gemma":0.000001156922,"domain_scores_codex":[0.9985232,0.0003164094,0.0002074253,0.0004238038,0.00015573,0.0003734123],"domain_scores_gemma":[0.9990242,0.0005405033,0.0000792988,0.0002185799,0.00002699895,0.0001103833],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009635185,0.00007370563,0.08888062,0.000005943,6.998798e-7,0.0003135631,0.00009606918,0.000002757539,0.9076213,0.0003901881,0.0002701196,0.002248749],"study_design_scores_gemma":[0.0004355197,0.001074865,0.03625491,0.000005451737,0.000008680821,0.002242487,0.00003009368,0.0002278087,0.9120114,0.0008945817,0.04664735,0.0001668271],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9986461,0.00006071686,0.000001940825,0.0004724254,0.0001432554,0.0001453439,9.986938e-7,0.0000406739,0.0004884801],"genre_scores_gemma":[0.996799,0.0009679905,0.00001955001,0.001412046,0.00003698851,0.000009507662,1.974104e-7,0.00001385693,0.0007408822],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05262571,"threshold_uncertainty_score":0.4180779,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0504542716505913,"score_gpt":0.3202023642243492,"score_spread":0.2697480925737579,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}