{"id":"W2030698401","doi":"10.1139/y07-026","title":"Hyperglycemia and hyperlipidemia are associated with endothelial dysfunction during the development of type 2 diabetes","year":2007,"lang":"en","type":"article","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Advanced Glycation End Products research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":50,"is_retracted":false,"has_abstract":true,"ca_institutions":"Child and Family Research Institute; St. Paul's Hospital; Centre for Advancing Health Outcomes; University of British Columbia","funders":"Heart and Stroke Foundation of British Columbia and Yukon; Association for Institutional Research; Heart and Stroke Foundation of Canada","keywords":"Internal medicine; Endocrinology; Endothelial dysfunction; Hyperinsulinemia; Hyperlipidemia; Diabetes mellitus; Type 2 diabetes; Medicine; Insulin; Endothelium; Cholesterol; Insulin resistance","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003561093,0.00007230384,0.0001307757,0.00006913979,0.0001447769,0.000002292211,0.00008001562,0.00008416732,0.000048236],"category_scores_gemma":[0.0001180643,0.00005043501,0.00001337598,0.00007621689,0.0002644206,0.000005698632,0.00001685927,0.000165565,3.630168e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002387001,"about_ca_system_score_gemma":0.0003455497,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00000917083,"about_ca_topic_score_gemma":0.0006566072,"domain_scores_codex":[0.9993833,0.0000830529,0.0001811418,0.0001083653,0.00004075258,0.0002034312],"domain_scores_gemma":[0.9993638,0.00006504003,0.0001774423,0.00005267962,0.0002091039,0.0001319534],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000260896,0.000007505923,0.02211833,0.00002149347,0.0001219463,0.000003114778,0.0001317728,0.0000645799,0.9763229,0.000005315598,0.00009970946,0.0008423849],"study_design_scores_gemma":[0.000747202,0.000279053,0.1819825,0.00001093285,0.00002383031,0.00003131017,0.0001155356,0.000004087199,0.8103732,0.00003669226,0.006325734,0.00006994278],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9986151,0.0009215509,0.00002803374,0.0001272263,0.0002082199,0.00005975262,0.00000526975,8.702498e-7,0.00003391415],"genre_scores_gemma":[0.9993001,0.00008248119,0.000147389,0.0001499578,0.000210916,0.000001298525,0.000006689614,0.000006964592,0.00009417041],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1659497,"threshold_uncertainty_score":0.205668,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01176875767723423,"score_gpt":0.2662881646054622,"score_spread":0.254519406928228,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}