{"id":"W2030882637","doi":"10.1158/1078-0432.ccr-06-0261","title":"Biological Markers for Non–Small Cell Lung Cancer Patient Selection for Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor Therapy","year":2006,"lang":"en","type":"review","venue":"Clinical Cancer Research","topic":"Lung Cancer Treatments and Mutations","field":"Medicine","cited_by":67,"is_retracted":false,"has_abstract":true,"ca_institutions":"Immunovaccine (Canada)","funders":"National Cancer Institute","keywords":"Epidermal growth factor receptor; Cancer research; Tyrosine kinase; Lung cancer; Tyrosine-kinase inhibitor; Epidermal growth factor; Cancer; Receptor tyrosine kinase; Receptor; Medicine; Biology; Oncology; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001221491,0.0006341736,0.002284593,0.0003381012,0.0004325247,0.00008323548,0.0002850851,0.0009769764,0.0005123345],"category_scores_gemma":[0.0006730236,0.0004200342,0.001497018,0.00070619,0.0003093549,0.00007237446,0.00009731282,0.00124585,0.00001710373],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00200608,"about_ca_system_score_gemma":0.004393639,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001232143,"about_ca_topic_score_gemma":0.0001854965,"domain_scores_codex":[0.9946173,0.0005971596,0.001652893,0.00140908,0.0005602171,0.001163336],"domain_scores_gemma":[0.9937983,0.003228049,0.0005116069,0.0004222442,0.001518295,0.0005215661],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001865602,0.001154383,0.003487315,0.01156914,0.0008189878,0.000005621742,0.00004051645,0.000001008852,0.00002518475,0.00001371287,0.1261598,0.8548588],"study_design_scores_gemma":[0.004959114,0.00399735,0.0004095382,0.004959586,0.0009053728,0.000002407897,0.00001737649,0.00006467078,0.0001906578,0.00001990048,0.9840208,0.000453238],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.004517688,0.9729114,0.0002237407,0.0007939396,0.001701518,0.01623344,0.003360241,0.00007918885,0.0001788475],"genre_scores_gemma":[0.0003955351,0.9640143,0.001443424,0.0002772762,0.004193386,0.02494371,0.001524377,0.0001815097,0.003026461],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.857861,"threshold_uncertainty_score":0.9998251,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2577402792836048,"score_gpt":0.5452083421699896,"score_spread":0.2874680628863848,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}