{"id":"W2030888690","doi":"10.1152/ajpgi.90376.2008","title":"Modulation of intestinal cholesterol absorption by high glucose levels: impact on cholesterol transporters, regulatory enzymes, and transcription factors","year":2008,"lang":"en","type":"article","venue":"American Journal of Physiology-Gastrointestinal and Liver Physiology","topic":"Cholesterol and Lipid Metabolism","field":"Medicine","cited_by":78,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre Hospitalier Universitaire Sainte-Justine","funders":"","keywords":"Internal medicine; Cholesterol; Endocrinology; Glucose transporter; ABCA1; Liver X receptor; Snf3; Chemistry; Carbohydrate metabolism; CD36; Biology; Insulin; Transporter; Biochemistry; Transcription factor; Medicine; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001348606,0.0002888933,0.0003506924,0.0001626596,0.0001134817,0.0005530867,0.00010883,0.0002260297,0.0009870972],"category_scores_gemma":[0.0001311105,0.0001056004,0.0002448784,0.00025261,0.0002791053,0.000199473,0.0001543981,0.0003761598,0.0001335526],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002663821,"about_ca_system_score_gemma":0.000158359,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007607423,"about_ca_topic_score_gemma":0.0007688188,"domain_scores_codex":[0.9998431,0.00004359001,0.00001202467,0.00002821147,0.00002403083,0.00004897565],"domain_scores_gemma":[0.9998729,0.00003132378,0.00002912011,0.00001481616,0.00001759648,0.00003423245],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001243842,0.00003640317,0.001387915,0.00006592013,0.00001276776,0.0001087725,0.00001838128,0.00003312305,0.9945978,0.000049473,0.00002246124,0.002423146],"study_design_scores_gemma":[0.00006650281,0.001097421,0.1018155,0.00001780195,0.0001096921,0.0003754269,0.0002415449,0.0008509397,0.8935527,0.0001222824,0.001735533,0.00001475203],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9939616,0.004097254,0.0008635423,0.0001436031,0.0000300686,0.000008521458,0.0001631843,0.00001758963,0.00071459],"genre_scores_gemma":[0.9960226,0.002062398,0.0008017645,0.00007577259,0.00002154378,0.00001900503,0.0001911731,0.00001013215,0.0007956139],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009870972,"threshold_uncertainty_score":0.003302097,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01446948506245779,"score_gpt":0.2350446523556352,"score_spread":0.2205751672931774,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}