{"id":"W2030896302","doi":"10.1016/j.bpj.2008.12.1868","title":"Mechanism Of Ion-ion And Ion-substrate Coupling In Secondary Amino-acid Transporters","year":2009,"lang":"en","type":"article","venue":"Biophysical Journal","topic":"Amino Acid Enzymes and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Chemistry; Ion; Selectivity; Molecular dynamics; Transporter; Substrate (aquarium); Membrane; Binding site; Coupling (piping); Biophysics; Computational chemistry; Biochemistry; Gene; Materials science; Organic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009698763,0.000439802,0.001344458,0.0005096348,0.0007301453,0.001802498,0.00153846,0.00176617,0.001940902],"category_scores_gemma":[0.0006615117,0.0004438543,0.00060777,0.0002445446,0.0009692703,0.003184479,0.000920026,0.001152393,0.001222149],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001206251,"about_ca_system_score_gemma":0.0004390114,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003872119,"about_ca_topic_score_gemma":0.0002255473,"domain_scores_codex":[0.9996961,0.00006302935,0.0000316005,0.00008260941,0.00006332928,0.000063343],"domain_scores_gemma":[0.9996055,0.000153084,0.00004866801,0.00004257322,0.00006995094,0.00008032192],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001037547,0.0001600375,0.001168537,0.0004339037,0.0000788127,0.001414966,0.0002815404,0.003884899,0.8957281,0.08446003,0.00108123,0.01027037],"study_design_scores_gemma":[0.000424283,0.001374159,0.00701647,0.00007763054,0.0001224042,0.003763625,0.0005890484,0.1611641,0.7555203,0.05754799,0.01219913,0.0002009142],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9017395,0.008997194,0.07254467,0.004948454,0.0006495718,0.000217544,0.0002459213,0.0007103143,0.009946746],"genre_scores_gemma":[0.9888868,0.002086888,0.004725108,0.0002549982,0.0001007485,0.00006547609,0.0001335488,0.00003619114,0.003710331],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001940902,"threshold_uncertainty_score":0.008751988,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007375972371690706,"score_gpt":0.2232527955017226,"score_spread":0.2158768231300319,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}