{"id":"W2030897912","doi":"10.1186/1471-2199-9-31","title":"Novel forms of Paired-like homeodomain transcription factor 2 (PITX2): Generation by alternative translation initiation and mRNA splicing","year":2008,"lang":"en","type":"article","venue":"BMC Molecular Biology","topic":"Developmental Biology and Gene Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":38,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; Vetenskapsrådet; National Institutes of Health; James N. Kirby Foundation; F. M. Kirby Foundation","keywords":"Alternative splicing; Biology; Gene isoform; RNA splicing; Transcription factor; Homeobox; Exon; Genetics; Messenger RNA; Intron; Translation (biology); Gene; Molecular biology; Cell biology; RNA","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001396454,0.0001789938,0.0001837066,0.00007870397,0.0001026491,0.000004927217,0.00007708864,0.0002937868,0.000007146843],"category_scores_gemma":[0.00002304632,0.0001709721,0.00007577443,0.00008137857,0.0001602182,0.00001389041,0.0000227559,0.00005923394,0.000001414768],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001746991,"about_ca_system_score_gemma":0.00004902569,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002180764,"about_ca_topic_score_gemma":0.00005474982,"domain_scores_codex":[0.9989297,0.0001151726,0.0003167321,0.0003762187,0.00007841182,0.0001837151],"domain_scores_gemma":[0.9995735,0.00001361494,0.0001583128,0.0001407971,0.00006549318,0.00004826064],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009631537,0.00004651761,0.007058567,0.00001346261,0.00004811029,5.110711e-7,0.0001618908,0.00006350908,0.9878289,0.00030911,0.00003142423,0.004341756],"study_design_scores_gemma":[0.001182345,0.0003691918,0.01553076,0.000007055025,0.00001659338,0.0000476512,0.00002316368,0.0006780537,0.9810793,0.0002769011,0.0005703078,0.0002187105],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7118737,0.0007651031,0.286885,0.00003120231,0.0001011945,0.0002131499,0.0000654115,0.000009016671,0.00005623532],"genre_scores_gemma":[0.9911227,0.0003184401,0.006012534,0.000144079,0.00006755419,0.00001866105,0.002267727,0.00001626839,0.00003205677],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2808725,"threshold_uncertainty_score":0.6972039,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02977788830781053,"score_gpt":0.2577567266841417,"score_spread":0.2279788383763311,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}