{"id":"W2030919445","doi":"10.1038/jid.2011.376","title":"TNFAIP3 Gene Polymorphisms Are Associated with Response to TNF Blockade in Psoriasis","year":2011,"lang":"en","type":"review","venue":"Journal of Investigative Dermatology","topic":"Psoriasis: Treatment and Pathogenesis","field":"Immunology and Microbiology","cited_by":173,"is_retracted":false,"has_abstract":false,"ca_institutions":"Toronto Western Hospital; University Health Network","funders":"National Institutes of Health; National Institute of Arthritis and Musculoskeletal and Skin Diseases; Arthritis Society; Canadian Institutes of Health Research; U.S. Department of Veterans Affairs","keywords":"Medicine; Psoriasis; Etanercept; Tumor necrosis factor alpha; Immunology; Rheumatoid arthritis; Psoriatic arthritis; Arthritis; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003182804,0.0004382916,0.001068665,0.0005290837,0.00008290797,0.0004140765,0.0003886955,0.0005184186,0.001105155],"category_scores_gemma":[0.0005390861,0.0001338874,0.0003597063,0.0008429599,0.0001738194,0.000298343,0.0001827241,0.0006689774,0.0004405998],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001696872,"about_ca_system_score_gemma":0.00030179,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004409754,"about_ca_topic_score_gemma":0.0006905734,"domain_scores_codex":[0.9998571,0.00002732026,0.00003565004,0.00002945295,0.00003934083,0.00001114599],"domain_scores_gemma":[0.9995812,0.0002301525,0.000106729,0.000009612101,0.00005288935,0.00001945197],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0007248274,0.00009467475,0.004514102,0.005541564,0.0003285729,0.000653304,0.00002476588,0.0002921984,0.004161752,0.0004982352,0.0100529,0.9731131],"study_design_scores_gemma":[0.000837849,0.001167936,0.09666832,0.007149253,0.005330037,0.02271684,0.0002431551,0.001333406,0.00589769,0.004682738,0.853866,0.0001069079],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001798608,0.996912,0.0002420509,0.0003461196,0.0001608481,0.000003049596,0.00002757492,0.00000624469,0.0005034896],"genre_scores_gemma":[0.0155583,0.9821032,0.0006134717,0.0003348942,0.0006806155,0.00001097878,0.00009789293,0.000002297874,0.0005983596],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001105155,"threshold_uncertainty_score":0.003697097,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05464714558623123,"score_gpt":0.278558151138154,"score_spread":0.2239110055519227,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}