{"id":"W2030978330","doi":"10.1038/nn.2951","title":"Emerging mechanisms of disrupted cellular signaling in brain ischemia","year":2011,"lang":"en","type":"article","venue":"Nature Neuroscience","topic":"Medicinal Plants and Bioactive Compounds","field":"Biochemistry, Genetics and Molecular Biology","cited_by":133,"is_retracted":false,"has_abstract":false,"ca_institutions":"University Health Network; University of Toronto","funders":"","keywords":"Excitotoxicity; Neuroscience; Glutamatergic; Mechanism (biology); Glutamate receptor; Ischemia; Biology; Psychology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004330951,0.0007528304,0.0006098973,0.0006268143,0.0004795685,0.001545711,0.000897194,0.001289048,0.001723782],"category_scores_gemma":[0.0002406133,0.0002647917,0.0003541871,0.0002574334,0.00133563,0.002007153,0.0005018387,0.001551594,0.0003235888],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007833272,"about_ca_system_score_gemma":0.0005217422,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002249388,"about_ca_topic_score_gemma":0.0003403313,"domain_scores_codex":[0.9998549,0.00002670451,0.000011901,0.00002888845,0.00002908162,0.0000484938],"domain_scores_gemma":[0.9998565,0.0000278724,0.0000494039,0.00001770992,0.00002207333,0.00002647648],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.001566213,0.0003243707,0.001533736,0.0009332825,0.00008906934,0.003581558,0.0003339509,0.001236516,0.8230894,0.1061744,0.003135755,0.0580018],"study_design_scores_gemma":[0.0003231381,0.002646188,0.02883555,0.0004349539,0.0004236154,0.008989355,0.001914492,0.008340159,0.6267797,0.2509209,0.0702488,0.00014309],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"review","genre_scores_codex":[0.5477055,0.3192494,0.07272244,0.03348058,0.001590877,0.0001676276,0.0008502218,0.0009147805,0.02331868],"genre_scores_gemma":[0.9035125,0.08023086,0.007989008,0.001775663,0.0007744075,0.0001107606,0.0002865522,0.00002584896,0.005294389],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.001723782,"threshold_uncertainty_score":0.00576669,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01424242785911637,"score_gpt":0.2590386240006091,"score_spread":0.2447961961414927,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}