{"id":"W2031012150","doi":"10.1016/j.neuron.2011.09.005","title":"An Imbalancing Act: Gap Junctions Reduce the Backward Motor Circuit Activity to Bias C. elegans for Forward Locomotion","year":2011,"lang":"en","type":"article","venue":"Neuron","topic":"Genetics, Aging, and Longevity in Model Organisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":286,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital","funders":"Canadian Institutes of Health Research","keywords":"Neuroscience; Caenorhabditis elegans; Interneuron; Directionality; Biological neural network; Gap junction; Electrical Synapses; Biology; Computer science; Inhibitory postsynaptic potential; Cell biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000378154,0.0008300589,0.0004602048,0.0003486076,0.000437995,0.0008921615,0.000772405,0.001060736,0.004837093],"category_scores_gemma":[0.0007045452,0.0003015237,0.0003408507,0.0001216865,0.0006536613,0.0009905116,0.000735411,0.001392885,0.0008407419],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004064225,"about_ca_system_score_gemma":0.0005033106,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004268261,"about_ca_topic_score_gemma":0.0008811291,"domain_scores_codex":[0.9997994,0.00002042766,0.00001790583,0.00006968882,0.00004999661,0.00004270112],"domain_scores_gemma":[0.9996499,0.00005222863,0.00007531467,0.0000627636,0.00006509381,0.00009474444],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001785318,0.0000689033,0.0002097043,0.0000821408,0.0000178577,0.00005615384,0.00001469639,0.0004659297,0.9906476,0.001741952,0.0003275551,0.006188934],"study_design_scores_gemma":[0.0001521457,0.0007822514,0.003967945,0.00003829258,0.000150213,0.0004741302,0.0000687248,0.01005561,0.9764637,0.002523083,0.005293869,0.00003009043],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9612123,0.001190411,0.02505855,0.001615443,0.0007331205,0.0000737669,0.0004229604,0.00114809,0.0085454],"genre_scores_gemma":[0.9859242,0.0004052138,0.008234857,0.0007457601,0.00006171832,0.00004890481,0.0001110985,0.0001546596,0.004313579],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004837093,"threshold_uncertainty_score":0.01618171,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07304845792035093,"score_gpt":0.2767142224067114,"score_spread":0.2036657644863605,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}