{"id":"W2031047943","doi":"10.1038/nm.3258","title":"Local proliferation dominates lesional macrophage accumulation in atherosclerosis","year":2013,"lang":"en","type":"article","venue":"Nature Medicine","topic":"Atherosclerosis and Cardiovascular Diseases","field":"Immunology and Microbiology","cited_by":1031,"is_retracted":false,"has_abstract":false,"ca_institutions":"Mount Sinai Hospital; University of Toronto; Lunenfeld-Tanenbaum Research Institute; Toronto General Hospital; University Health Network","funders":"National Institute of Allergy and Infectious Diseases; National Institute of Diabetes and Digestive and Kidney Diseases; National Cancer Institute; National Heart, Lung, and Blood Institute; U.S. Public Health Service","keywords":"Macrophage; Monocyte; Scavenger receptor; Infiltration (HVAC); Immunology; Cell biology; Inflammation; Foam cell; Biology; Cancer research; Cholesterol; Endocrinology; Lipoprotein; In vitro; Materials science","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005675861,0.0003454636,0.0005824385,0.0007920883,0.0004078967,0.0009382506,0.0001931625,0.0006179779,0.002582201],"category_scores_gemma":[0.000418573,0.0003247518,0.0001963393,0.0002646569,0.0004591976,0.0005234872,0.0005468704,0.0007563031,0.001035243],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002160635,"about_ca_system_score_gemma":0.0002228709,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002319985,"about_ca_topic_score_gemma":0.0005940277,"domain_scores_codex":[0.9996381,0.00009628085,0.00001679351,0.00005383023,0.00007737409,0.0001176423],"domain_scores_gemma":[0.999706,0.00005591724,0.00004800036,0.00002746128,0.00005094227,0.0001117164],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001238966,0.0001097768,0.005994949,0.0001800706,0.00001190589,0.0003308604,0.0001135372,0.0001588916,0.9788153,0.0008316129,0.0002463582,0.01196779],"study_design_scores_gemma":[0.0003141308,0.002864881,0.2804082,0.0002342676,0.0003041816,0.004872878,0.002355446,0.006445141,0.6798729,0.006390695,0.01586175,0.00007554059],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.985287,0.007851639,0.002332388,0.000298506,0.00006412104,0.00001444204,0.00005414808,0.00008175313,0.004015977],"genre_scores_gemma":[0.9936197,0.001776111,0.0007641397,0.000126561,0.0002386153,0.00001839718,0.00005362338,0.00002527796,0.003377411],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002582201,"threshold_uncertainty_score":0.008638322,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01282251714371733,"score_gpt":0.2632748832242828,"score_spread":0.2504523660805655,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}