{"id":"W2031075632","doi":"10.1038/nchem.1367","title":"An ultrasensitive universal detector based on neutralizer displacement","year":2012,"lang":"en","type":"article","venue":"Nature Chemistry","topic":"Advanced biosensing and bioanalysis techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":200,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Analyte; Chemistry; Biomolecule; Aptamer; Nucleic acid; Small molecule; Molecule; Nanotechnology; Analytical Chemistry (journal); Chromatography; Biochemistry; Organic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001535645,0.001484127,0.001177739,0.001140772,0.000799184,0.0009193645,0.003325565,0.001774906,0.002622182],"category_scores_gemma":[0.0008195158,0.0009708839,0.0004511407,0.0007306213,0.00101117,0.001373774,0.001827749,0.00153792,0.001626679],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001156021,"about_ca_system_score_gemma":0.001300697,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005608778,"about_ca_topic_score_gemma":0.00113383,"domain_scores_codex":[0.9979473,0.0002073571,0.00009645021,0.0007479198,0.0007823365,0.0002186074],"domain_scores_gemma":[0.9994177,0.0002202235,0.00006324563,0.00006814064,0.0001389853,0.00009167812],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001052836,0.0000409909,0.0003069603,0.0001212775,0.00001172359,0.00004606876,0.00005810595,0.00006870997,0.9764355,0.00226057,0.0006431114,0.01990176],"study_design_scores_gemma":[0.00001841584,0.0001667352,0.0003999473,0.000006173783,0.00002200154,0.0003341046,0.00001602416,0.002775488,0.9853235,0.0002699708,0.01063581,0.00003186609],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"empirical","genre_scores_codex":[0.2076479,0.00748085,0.7596788,0.001176648,0.001602466,0.001155368,0.0009773487,0.00891489,0.01136557],"genre_scores_gemma":[0.4407257,0.002522667,0.5232417,0.001410208,0.0003048473,0.0007125209,0.001260499,0.0002827636,0.02953913],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.003325565,"threshold_uncertainty_score":0.008772075,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003747764827830952,"score_gpt":0.2660252076669183,"score_spread":0.2622774428390874,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}