{"id":"W2031077701","doi":"10.1128/jvi.02848-13","title":"The Human Metapneumovirus Small Hydrophobic Protein Has Properties Consistent with Those of a Viroporin and Can Modulate Viral Fusogenic Activity","year":2014,"lang":"en","type":"article","venue":"Journal of Virology","topic":"Respiratory viral infections research","field":"Medicine","cited_by":55,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Allergy and Infectious Diseases; National Institutes of Health; Howard Hughes Medical Institute; Centre Hospitalier Universitaire de Québec; National Center for Research Resources; American Heart Association","keywords":"Biology; Human metapneumovirus; Glycoprotein; Transmembrane protein; Fusion protein; Lipid bilayer fusion; Vesicle-associated membrane protein 8; Membrane glycoproteins; Transmembrane domain; Cell biology; Viral entry; Membrane protein; Biochemistry; Virology; Virus; Membrane; Viral replication; Receptor; Respiratory tract infections; Respiratory system","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006630679,0.0001997139,0.00009711448,0.00006872661,0.00009562022,0.0001365863,0.00007573817,0.0002262574,0.0009847634],"category_scores_gemma":[0.0001098492,0.00004375081,0.0001508594,0.00007095739,0.0002109007,0.0001092518,0.0001234745,0.0001636066,0.0002115727],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001664574,"about_ca_system_score_gemma":0.00007613405,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001856556,"about_ca_topic_score_gemma":0.0001855055,"domain_scores_codex":[0.9999532,0.000009069832,0.000002850555,0.00001109384,0.0000125883,0.00001114711],"domain_scores_gemma":[0.9999526,0.0000142854,0.00001133568,0.000004712046,0.000004631747,0.00001248142],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004965571,0.000007415854,0.000245692,0.00002055093,0.000002393348,0.00004356935,0.000004326686,0.00002993402,0.9986994,0.00005817627,0.00001613446,0.0008227064],"study_design_scores_gemma":[0.00001539398,0.0005382663,0.0139696,0.000008114544,0.00001576239,0.001066809,0.00002838722,0.0007373095,0.9798251,0.00009382862,0.003697706,0.000003680314],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9940814,0.00177192,0.002211195,0.00009786694,0.00001884406,0.00002659405,0.0001772283,0.00003378274,0.001581114],"genre_scores_gemma":[0.9970073,0.0004909002,0.001305438,0.00003775301,0.000009145783,0.00002026621,0.0002294143,0.000007896816,0.0008918659],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009847634,"threshold_uncertainty_score":0.003294349,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.073739892084378,"score_gpt":0.3082407439301408,"score_spread":0.2345008518457628,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}