{"id":"W2031117040","doi":"10.1002/jgm.666","title":"Use of a murine secreted alkaline phosphatase as a non‐immunogenic reporter gene in mice","year":2004,"lang":"en","type":"article","venue":"The Journal of Gene Medicine","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary; McMaster University; University of Ottawa","funders":"Canadian Institutes of Health Research","keywords":"Reporter gene; Placental alkaline phosphatase; Biology; Molecular biology; Alkaline phosphatase; Transgene; In vivo; Gene expression; Gene delivery; Antibody; Gene; Genetic enhancement; Immunology; Biochemistry; Genetics; Enzyme","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001705792,0.00198984,0.0007216735,0.002364391,0.00042434,0.001129995,0.001886553,0.001838705,0.0043973],"category_scores_gemma":[0.0004250345,0.0008722349,0.001255122,0.0008341729,0.001030389,0.00106965,0.0006471102,0.002859371,0.002411824],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008045412,"about_ca_system_score_gemma":0.000836262,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004264771,"about_ca_topic_score_gemma":0.0005416204,"domain_scores_codex":[0.9984944,0.0002304084,0.0001991106,0.0004702044,0.0003958306,0.0002100834],"domain_scores_gemma":[0.9988294,0.0001892098,0.0003978334,0.0002054944,0.0001661557,0.0002119246],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002248539,0.0001364064,0.0001673891,0.0001438398,0.0000168007,0.00006499042,0.00004639082,0.000113107,0.9949393,0.0006841916,0.0001645796,0.00329808],"study_design_scores_gemma":[0.00009042752,0.0008275328,0.0006226734,0.00004108228,0.00004549588,0.0003700524,0.00002092654,0.0007999575,0.9886305,0.0001268412,0.008412259,0.00001222194],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.6192389,0.007737747,0.3418541,0.001492211,0.0009328348,0.002683313,0.00655224,0.004898428,0.01461021],"genre_scores_gemma":[0.6739421,0.008920881,0.2577332,0.0005488893,0.0002167077,0.005694491,0.01162639,0.001068207,0.04024908],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0043973,"threshold_uncertainty_score":0.01471043,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02465468265624574,"score_gpt":0.3074307764102787,"score_spread":0.282776093754033,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}