{"id":"W2031117040","doi":"10.1002/jgm.666","title":"Use of a murine secreted alkaline phosphatase as a non‐immunogenic reporter gene in mice","year":2004,"lang":"en","type":"article","venue":"The Journal of Gene Medicine","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary; McMaster University; University of Ottawa","funders":"Canadian Institutes of Health Research","keywords":"Reporter gene; Placental alkaline phosphatase; Biology; Molecular biology; Alkaline phosphatase; Transgene; In vivo; Gene expression; Gene delivery; Antibody; Gene; Genetic enhancement; Immunology; Biochemistry; Genetics; Enzyme","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001897795,0.0001940394,0.0004094363,0.0001794349,0.0000410715,0.000005566867,0.0004497255,0.0001015763,0.000115227],"category_scores_gemma":[0.0003738751,0.0001234502,0.0001209633,0.0003290435,0.0002462831,0.000009731453,0.0000888898,0.0002575526,0.000004980796],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005334318,"about_ca_system_score_gemma":0.000374866,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000451002,"about_ca_topic_score_gemma":0.0002390095,"domain_scores_codex":[0.9979448,0.000180156,0.0009139432,0.0001714812,0.0004952146,0.0002943896],"domain_scores_gemma":[0.9982949,0.00004552563,0.0005801158,0.0005756374,0.0003659512,0.0001378251],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.008131139,0.000131271,0.0001526431,0.00001599552,0.0002245562,0.0002046422,0.0002988421,0.001284448,0.9881207,0.000001123774,0.0005725098,0.0008620791],"study_design_scores_gemma":[0.004493256,0.00755922,0.0006763897,0.0001149014,0.00009762878,0.00146962,0.0001115314,0.00002757468,0.9835107,0.00007099724,0.001750636,0.0001175069],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9868948,0.0107766,0.0004943843,0.001431686,0.0001259497,0.0002366397,0.00001326554,0.000002300912,0.00002436596],"genre_scores_gemma":[0.9936334,0.004238111,0.0006014941,0.0007913006,0.0004226009,0.000003492883,0.00005814899,0.00003303951,0.0002183825],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007427949,"threshold_uncertainty_score":0.5034152,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02465468265624574,"score_gpt":0.3074307764102787,"score_spread":0.282776093754033,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}