{"id":"W2031141630","doi":"10.1038/bmt.2009.335","title":"Genetic polymorphisms associated with outcome in multiple myeloma patients receiving high-dose melphalan","year":2009,"lang":"en","type":"article","venue":"Bone Marrow Transplantation","topic":"Multiple Myeloma Research and Treatments","field":"Medicine","cited_by":45,"is_retracted":false,"has_abstract":false,"ca_institutions":"Alberta Cancer Foundation","funders":"Ministero dell’Istruzione, dell’Università e della Ricerca","keywords":"Single-nucleotide polymorphism; Medicine; Melphalan; XRCC1; Genotyping; Oncology; Mucositis; Internal medicine; Haplotype; Pharmacogenetics; Genotype; Multiple myeloma; Genetics; Toxicity; Biology; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003194048,0.0003164052,0.0004449628,0.000487788,0.0004439987,0.0005335532,0.0002945628,0.0006147854,0.001428717],"category_scores_gemma":[0.00136527,0.0001717082,0.0005212449,0.0008846759,0.0002783047,0.0002357594,0.0002203869,0.000853891,0.0001803839],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003233317,"about_ca_system_score_gemma":0.0003126552,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00174439,"about_ca_topic_score_gemma":0.001551935,"domain_scores_codex":[0.9996408,0.0001182912,0.00004302817,0.00005375158,0.00004892784,0.00009508556],"domain_scores_gemma":[0.9987375,0.0003801883,0.0004527578,0.00005478566,0.00005933077,0.0003154748],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.004909366,0.0003570461,0.9806783,0.00001651189,0.0004199737,0.00116801,0.0001153715,0.0002940207,0.00861193,0.00008541741,0.0001905536,0.003153542],"study_design_scores_gemma":[0.0001280127,0.0005976568,0.9957592,0.000007056649,0.0002517595,0.00132825,0.0001086436,0.0006522508,0.0007880562,0.0001498021,0.0002192694,0.000010164],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9994996,0.0001298077,0.00004297907,0.00006502712,0.000009377806,0.000001998641,0.00004485077,0.00000247269,0.0002039158],"genre_scores_gemma":[0.9997517,0.00003272164,0.00002675103,0.00002677096,0.00001254952,0.000002060055,0.00004719611,0.00000194071,0.00009830661],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00174439,"threshold_uncertainty_score":0.004779577,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02085842810874624,"score_gpt":0.2614323060831349,"score_spread":0.2405738779743887,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}