{"id":"W2031191883","doi":"10.1158/1538-7445.am2013-lb-67","title":"Abstract LB-67: REGARD: A phase III, randomized, double-blind trial of ramucirumab and best supportive care (BSC) versus placebo and BSC in the treatment of metastatic gastric or gastroesophageal junction (GEJ) adenocarcinoma following disease progression on first-line p","year":2013,"lang":"en","type":"article","venue":"Cancer Research","topic":"Gastric Cancer Management and Outcomes","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hôpital Notre-Dame","funders":"","keywords":"Ramucirumab; Medicine; Internal medicine; Hazard ratio; Clinical endpoint; Placebo; Gastroenterology; Cancer; Progression-free survival; Bevacizumab; Oncology; Randomized controlled trial; Chemotherapy; Confidence interval; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00169764,0.001938925,0.002505718,0.0005061007,0.0004586092,0.001033932,0.001001919,0.001985979,0.00735379],"category_scores_gemma":[0.001282099,0.0008928087,0.00134539,0.0003491952,0.001422634,0.000823279,0.0003560034,0.003557587,0.001412474],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007100472,"about_ca_system_score_gemma":0.001462571,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001048675,"about_ca_topic_score_gemma":0.002235125,"domain_scores_codex":[0.9995308,0.000275999,0.00002536824,0.00006306185,0.00003059201,0.00007417454],"domain_scores_gemma":[0.999396,0.000139497,0.0001355241,0.0000348033,0.00003284181,0.0002612218],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9758591,0.008882212,0.0003681652,0.0004116984,0.0003347615,0.00003265932,0.00003492811,0.0001987942,0.003988113,0.00008662384,0.0008024713,0.009000491],"study_design_scores_gemma":[0.9301591,0.06819751,0.0006042495,0.00002282359,0.0001823208,0.00001883766,0.00001052085,0.0001975434,0.0002792022,0.00004475209,0.0002759307,0.000007284455],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9863782,0.003695353,0.0005984372,0.0007843636,0.0005277051,0.004127079,0.001067827,0.0002122211,0.002608774],"genre_scores_gemma":[0.9850687,0.002409163,0.001368596,0.001334832,0.0005595793,0.004392123,0.001236021,0.00003111268,0.00359991],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00735379,"threshold_uncertainty_score":0.02460086,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1331793739946357,"score_gpt":0.4416337284529729,"score_spread":0.3084543544583372,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}