{"id":"W2031274429","doi":"10.4161/chim.23350","title":"Toward minimal conditioning protocols for allogeneic chimerism in tolerance resistant recipients","year":2012,"lang":"en","type":"article","venue":"Chimerism","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Diabetes Canada; University of Alberta","funders":"Edmonton Civic Employees Charitable Assistance Fund; Alberta Innovates - Health Solutions","keywords":"Nod; Immunology; Clonal deletion; Immune tolerance; NOD mice; Cyclophosphamide; Transplantation Chimera; Biology; Medicine; Antibody; T cell; Antigen; Immune system; Stem cell; Haematopoiesis; Autoimmunity; T-cell receptor; Diabetes mellitus; Chemotherapy; Genetics; Hematopoietic cell","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008796792,0.0003898338,0.0002378799,0.0003800417,0.0002838934,0.0003280703,0.0004904575,0.0003045712,0.00130357],"category_scores_gemma":[0.0004089885,0.0001680069,0.0002245696,0.0001602302,0.000314737,0.0002980184,0.0003966865,0.00123503,0.0002704204],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002834574,"about_ca_system_score_gemma":0.0003112817,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002220081,"about_ca_topic_score_gemma":0.0004509391,"domain_scores_codex":[0.9996827,0.0001020766,0.0000283776,0.00004429494,0.000103186,0.0000393872],"domain_scores_gemma":[0.9997537,0.00006433678,0.0000654035,0.00003939022,0.00003623596,0.00004097701],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008407321,0.00008846572,0.00007585024,0.00005566797,0.00000439913,0.00002288532,0.00004338061,0.0004556884,0.99296,0.001173416,0.00009513406,0.004940991],"study_design_scores_gemma":[0.00002730916,0.0005123868,0.0004118442,0.00001938498,0.00001950135,0.0001623453,0.000011962,0.001422579,0.9922512,0.0003571496,0.004797641,0.000006573792],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.6946601,0.0034215,0.293839,0.0004318534,0.00009761992,0.001370702,0.0003119626,0.0005837249,0.005283485],"genre_scores_gemma":[0.8314979,0.002361619,0.1606816,0.000246575,0.0000463557,0.0008632205,0.0004742919,0.000152491,0.003675955],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00130357,"threshold_uncertainty_score":0.004652202,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03816653581721131,"score_gpt":0.2979626844590962,"score_spread":0.2597961486418849,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}