{"id":"W2031280751","doi":"10.1182/blood-2014-02-557975","title":"Phosphoinositide 3-kinase β mediates microvascular endothelial repair of thrombotic microangiopathy","year":2014,"lang":"en","type":"article","venue":"Blood","topic":"Complement system in diseases","field":"Immunology and Microbiology","cited_by":23,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research","keywords":"Thrombotic microangiopathy; Phosphoinositide 3-kinase; Medicine; Endothelium; Internal medicine; Cell biology; Biology; Signal transduction; PI3K/AKT/mTOR pathway","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003224815,0.0002017214,0.0004231453,0.00008961689,0.00009172357,0.000006939958,0.0002925897,0.0001086799,0.000684895],"category_scores_gemma":[0.0001780486,0.0001868468,0.0003695168,0.0000963881,0.0001802249,0.00004359701,0.0001228703,0.00009574427,0.0004698114],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001272978,"about_ca_system_score_gemma":0.00004315983,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001784985,"about_ca_topic_score_gemma":0.00001874305,"domain_scores_codex":[0.998549,0.0002756366,0.0004355993,0.0003326526,0.00005740949,0.0003496965],"domain_scores_gemma":[0.9989039,0.0002227467,0.000173911,0.0005924889,0.00007463509,0.00003231471],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003469184,0.0006980633,0.05138822,0.0001148126,0.0005503438,0.000008183954,0.0001683708,0.000001597315,0.9439832,0.0005961762,0.002280594,0.0001757561],"study_design_scores_gemma":[0.003493551,0.0002253171,0.02421437,0.0001017278,0.0004625666,0.00005951383,0.0000964876,0.000001638459,0.9626052,0.0001580081,0.008367178,0.0002144763],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9897552,0.008481817,0.00005466291,0.00002735431,0.0004949444,0.000297771,0.0001028649,0.0001752901,0.0006101431],"genre_scores_gemma":[0.9991491,0.00003783759,0.0002987653,0.00007964561,0.00007674186,0.00002943945,0.0001079316,0.00002555284,0.0001949136],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02717384,"threshold_uncertainty_score":0.7619392,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006817359613016385,"score_gpt":0.2067358979165146,"score_spread":0.1999185383034982,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}