{"id":"W2031283370","doi":"10.1016/j.intimp.2010.11.015","title":"Consequences of double negative regulatory T cell and antigen presenting cell interaction on immune response suppression","year":2010,"lang":"en","type":"article","venue":"International Immunopharmacology","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":17,"is_retracted":false,"has_abstract":false,"ca_institutions":"University Health Network; University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"CD80; CD86; Immunology; Antigen-presenting cell; T cell; Antigen; Immune system; Cell biology; CD8; Chemistry; Biology; Cytotoxic T cell; CD40; In vitro","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006476766,0.000647162,0.0005913371,0.0003897443,0.0003159715,0.0007318018,0.0005528445,0.0007811897,0.004013816],"category_scores_gemma":[0.0007011911,0.0002480657,0.0003230356,0.0001228859,0.0005087652,0.0003770807,0.000409721,0.001132042,0.0005787978],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002156498,"about_ca_system_score_gemma":0.0003004175,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009321276,"about_ca_topic_score_gemma":0.00009499167,"domain_scores_codex":[0.9992879,0.0002019541,0.0000430548,0.00009643933,0.0001310422,0.0002396792],"domain_scores_gemma":[0.9992186,0.0002910709,0.00009905086,0.0001014191,0.00004834274,0.0002414091],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00213583,0.0001156323,0.0009622742,0.00002503867,0.000009837654,0.0004911401,0.00001432117,0.0001573747,0.9925916,0.0006903055,0.00005741852,0.002749269],"study_design_scores_gemma":[0.0004706397,0.002161135,0.01371949,0.00001096868,0.0001139897,0.003547981,0.00009375875,0.004230177,0.9718049,0.001915114,0.001912574,0.00001926038],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9952967,0.0004953796,0.00122878,0.0001217945,0.00008568192,0.00001472356,0.0000385494,0.00005241263,0.002666033],"genre_scores_gemma":[0.9983029,0.00007440693,0.0006235092,0.00007058762,0.00005491878,0.00001582462,0.00004134834,0.00001599841,0.0008004608],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004013816,"threshold_uncertainty_score":0.0134275,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01392266446050091,"score_gpt":0.2891633330023891,"score_spread":0.2752406685418882,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}