{"id":"W2031283370","doi":"10.1016/j.intimp.2010.11.015","title":"Consequences of double negative regulatory T cell and antigen presenting cell interaction on immune response suppression","year":2010,"lang":"en","type":"article","venue":"International Immunopharmacology","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":17,"is_retracted":false,"has_abstract":false,"ca_institutions":"University Health Network; University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"CD80; CD86; Immunology; Antigen-presenting cell; T cell; Antigen; Immune system; Cell biology; CD8; Chemistry; Biology; Cytotoxic T cell; CD40; In vitro","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0005474795,0.0002728271,0.0003765809,0.0003635876,0.0002270278,0.00002464023,0.0005361083,0.0004053083,0.002240331],"category_scores_gemma":[0.00009108087,0.000250714,0.0001203704,0.0001045136,0.001043413,0.0002374843,0.0003110861,0.0009615046,0.0002583251],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004502405,"about_ca_system_score_gemma":0.0001102221,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002943487,"about_ca_topic_score_gemma":0.000007473814,"domain_scores_codex":[0.9980691,0.0003986749,0.0006289639,0.0004536391,0.00008663916,0.0003629872],"domain_scores_gemma":[0.9979329,0.0009296988,0.0005526785,0.0002949496,0.0002608106,0.00002899949],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.008231953,0.0004739633,0.001266032,0.00001651482,0.0002212288,0.00001982779,0.0006436468,0.00001745594,0.9870149,0.0004673576,0.001235413,0.0003917058],"study_design_scores_gemma":[0.004807559,0.0003486427,0.0081238,0.00002498774,0.00003980007,0.0001248265,0.0003371916,0.00001302992,0.9624509,0.0001696134,0.02334606,0.0002136383],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9836792,0.0007994758,0.000004806295,0.0007548013,0.008005677,0.0003249955,0.00003845425,0.00006030977,0.006332303],"genre_scores_gemma":[0.9926556,0.0002465446,0.0001044131,0.0001346618,0.00006483541,0.00004201309,0.00006822843,0.00002482288,0.006658924],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02456405,"threshold_uncertainty_score":0.9999945,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01392266446050091,"score_gpt":0.2891633330023891,"score_spread":0.2752406685418882,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}