{"id":"W2031293088","doi":"10.1073/pnas.0604983103","title":"Phosphorylation and cleavage of presenilin-associated rhomboid-like protein (PARL) promotes changes in mitochondrial morphology","year":2006,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":95,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa; Université Laval","funders":"","keywords":"Mitochondrial fission; Cell biology; mitochondrial fusion; Biology; Rhomboid; Phosphorylation; Mitochondrion; Inner mitochondrial membrane; Presenilin; Mitochondrial apoptosis-induced channel; Mitochondrial carrier; Cleavage (geology); Mitochondrial DNA; Biochemistry; Bacterial outer membrane; Proteases","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005114209,0.00008064511,0.0001481755,0.000102256,0.00005645979,0.000005958552,0.0002300248,0.0001824428,0.000005395159],"category_scores_gemma":[0.0004829968,0.0000615492,0.0000369689,0.0002890225,0.000554956,0.00001453208,0.00009461173,0.00008739711,1.889723e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000008866858,"about_ca_system_score_gemma":0.0000261595,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004065348,"about_ca_topic_score_gemma":0.000008496899,"domain_scores_codex":[0.9990344,0.00002026316,0.0002753954,0.0002404188,0.0003101779,0.000119324],"domain_scores_gemma":[0.9994108,0.00002703477,0.0003812598,0.00001025889,0.0001553453,0.00001527538],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000755603,0.00005779595,0.012078,0.00002381865,0.000005773515,7.406201e-9,0.0000378427,0.00001506305,0.9843839,0.002666718,0.0005929586,0.00006257687],"study_design_scores_gemma":[0.0003839998,0.0001840378,0.05736113,0.00002942121,0.000005535477,0.000003976784,0.00003326153,0.00008054268,0.9371841,0.004494309,0.0001811576,0.00005850731],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9975082,0.0001604814,0.000002762999,0.000867175,0.00004070823,0.0003254359,0.00001860389,0.000003162211,0.001073429],"genre_scores_gemma":[0.9984832,0.00001834725,0.0009343597,0.0000559408,0.00009998328,0.00001967521,0.000002111893,0.000003769525,0.0003825544],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04719976,"threshold_uncertainty_score":0.2509904,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01948904947246557,"score_gpt":0.2613652396692768,"score_spread":0.2418761901968113,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}