{"id":"W2031388575","doi":"10.1038/nsmb.2357","title":"RNA cytosine methylation by Dnmt2 and NSun2 promotes tRNA stability and protein synthesis","year":2012,"lang":"en","type":"article","venue":"Nature Structural & Molecular Biology","topic":"RNA modifications and cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":658,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Deutsche Forschungsgemeinschaft; Institute of Genetics; Wellcome Trust; Deutsches Krebsforschungszentrum","keywords":"Transfer RNA; Methylation; Cytosine; Methyltransferase; Biology; DNA methylation; RNA; Protein biosynthesis; Genetics; Molecular biology; Biochemistry; DNA; Gene; Gene expression","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002307937,0.0002723656,0.0002291223,0.0001226218,0.000283174,0.0004767126,0.0002289904,0.0002925299,0.002524138],"category_scores_gemma":[0.0002988381,0.0002500008,0.0002558146,0.0001009401,0.0002396439,0.000416483,0.000420493,0.0005855363,0.0005474855],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006081188,"about_ca_system_score_gemma":0.0003320948,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001139374,"about_ca_topic_score_gemma":0.003130641,"domain_scores_codex":[0.9998643,0.00001691605,0.000009879434,0.00004729586,0.00003286851,0.00002869164],"domain_scores_gemma":[0.9998686,0.00002389111,0.00002558627,0.00002426975,0.00001923717,0.00003842885],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002231104,0.000009476891,0.0003990662,0.00002186671,0.00000794632,0.00002663658,0.00001304618,0.00009040657,0.9964187,0.0003122058,0.00008792189,0.002389615],"study_design_scores_gemma":[0.000009382114,0.00003977829,0.001858038,0.000001822542,0.000004493073,0.00007053261,0.0000115586,0.0008859081,0.99544,0.00009360589,0.001581731,0.000003178661],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9854596,0.002777033,0.007001676,0.0003245852,0.0001064571,0.00001891642,0.0003399088,0.0002976701,0.003674127],"genre_scores_gemma":[0.9925511,0.000300574,0.002814009,0.00004541829,0.00001363637,0.000008536203,0.0003344599,0.0000524321,0.003880016],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002524138,"threshold_uncertainty_score":0.008444071,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005655001948243068,"score_gpt":0.2742470730789596,"score_spread":0.2685920711307165,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}