{"id":"W2031485413","doi":"10.1002/ajmg.10696","title":"Chromosome and gene alterations in breast cancer as markers for diagnosis and prognosis as well as pathogenetic targets for therapy","year":2002,"lang":"en","type":"review","venue":"American Journal of Medical Genetics","topic":"Genomic variations and chromosomal abnormalities","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Cancer Research","funders":"","keywords":"Breast cancer; Carcinogenesis; Malignancy; Biology; Disease; Cancer; Cytogenetics; Comparative genomic hybridization; Targeted therapy; Cancer research; Gene; Gene expression profiling; Bioinformatics; Chromosome; Genetics; Pathology; Medicine; Gene expression","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009497794,0.0009442132,0.001686521,0.002649572,0.0003078182,0.0008419561,0.001112214,0.001490195,0.002780052],"category_scores_gemma":[0.001222434,0.000249369,0.0003365783,0.002765249,0.0007168941,0.001264418,0.0004635137,0.001627773,0.002987342],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007344238,"about_ca_system_score_gemma":0.000898869,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001131435,"about_ca_topic_score_gemma":0.001919277,"domain_scores_codex":[0.9997151,0.00007132645,0.00003352284,0.0000361789,0.0001238868,0.00001985009],"domain_scores_gemma":[0.9993831,0.0002656695,0.00005846346,0.00002142727,0.0002143437,0.00005695583],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001154577,0.00009264795,0.0005383,0.005202921,0.00006627822,0.0006347348,0.00004974325,0.0003959952,0.001445341,0.003173731,0.04150608,0.9467787],"study_design_scores_gemma":[0.00002776914,0.00009218454,0.002141623,0.0020469,0.00008532672,0.004690218,0.00007982001,0.0001207492,0.00044016,0.002810353,0.9874437,0.00002110907],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001157166,0.9976584,0.0002108319,0.0005237595,0.0003909261,0.000005522261,0.0000102087,0.000007731021,0.00107697],"genre_scores_gemma":[0.0008026253,0.9972702,0.0004099587,0.0002576155,0.0003791198,0.000007461016,0.00001947779,0.000001366621,0.0008522012],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002780052,"threshold_uncertainty_score":0.009300172,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01783616009758869,"score_gpt":0.3069321795152622,"score_spread":0.2890960194176735,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}