{"id":"W2031539920","doi":"10.7164/antibiotics.53.1145","title":"Enhanced Production of Microbial Metabolites in the Presence of Dimethyl Sulfoxide.","year":2000,"lang":"en","type":"article","venue":"The Journal of Antibiotics","topic":"Microbial Natural Products and Biosynthesis","field":"Medicine","cited_by":63,"is_retracted":false,"has_abstract":true,"ca_institutions":"TerraBioGen (Canada)","funders":"","keywords":"Polyketide; Metabolite; Dimethyl sulfoxide; Biochemistry; Secondary metabolite; Thiostrepton; Chemistry; Streptomyces; Chloramphenicol; Bacillus circulans; Bacteria; Biosynthesis; Fermentation; Actinomycetales; Antibiotics; Microbial metabolism; Tryptophan; Microbiology; Biology; Enzyme; Amino acid; Organic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001501533,0.00008870379,0.0003335515,0.00008347356,0.00002857447,0.000005169361,0.0002439641,0.00004990345,0.0000707639],"category_scores_gemma":[0.0005374784,0.00003927923,0.0001033382,0.0003575461,0.0002035874,0.00007463818,0.00001501591,0.0002742967,0.000001918739],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000009309346,"about_ca_system_score_gemma":0.00006140913,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003557307,"about_ca_topic_score_gemma":0.000007150393,"domain_scores_codex":[0.99883,0.0001918464,0.0005377329,0.00007286896,0.0002441218,0.0001234631],"domain_scores_gemma":[0.9989446,0.0001654929,0.0003686889,0.0002525741,0.0002482782,0.00002036158],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006391808,0.0002028072,0.0001738562,0.00008200541,0.0000503267,0.000002452664,0.001016288,0.00004145092,0.9917686,0.00002383549,0.0007609348,0.005238248],"study_design_scores_gemma":[0.0002918387,0.0002359166,0.007119881,0.0002480827,0.0002092304,0.0001690307,0.0002630561,0.000004415869,0.9905528,0.00005132228,0.0008132141,0.00004119392],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9945595,0.001291556,0.000008468576,0.003592243,0.0001960459,0.0001947895,0.000003335863,0.0000017744,0.0001522429],"genre_scores_gemma":[0.9959894,0.002552944,0.0006942023,0.00008872095,0.0002791715,1.099728e-9,5.480895e-7,0.000006247672,0.0003887156],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006946025,"threshold_uncertainty_score":0.1601761,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01227420977592395,"score_gpt":0.2521808789341722,"score_spread":0.2399066691582483,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}