{"id":"W2031539920","doi":"10.7164/antibiotics.53.1145","title":"Enhanced Production of Microbial Metabolites in the Presence of Dimethyl Sulfoxide.","year":2000,"lang":"en","type":"article","venue":"The Journal of Antibiotics","topic":"Microbial Natural Products and Biosynthesis","field":"Medicine","cited_by":63,"is_retracted":false,"has_abstract":true,"ca_institutions":"TerraBioGen (Canada)","funders":"","keywords":"Polyketide; Metabolite; Dimethyl sulfoxide; Biochemistry; Secondary metabolite; Thiostrepton; Chemistry; Streptomyces; Chloramphenicol; Bacillus circulans; Bacteria; Biosynthesis; Fermentation; Actinomycetales; Antibiotics; Microbial metabolism; Tryptophan; Microbiology; Biology; Enzyme; Amino acid; Organic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004114682,0.0006773275,0.000474089,0.0002758921,0.0001194824,0.0003756414,0.0002551195,0.0003038815,0.0006196337],"category_scores_gemma":[0.0005308049,0.000160806,0.0002579292,0.0002455532,0.0002457324,0.0003586852,0.0003636149,0.0005191094,0.0002912045],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002153125,"about_ca_system_score_gemma":0.0002923047,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003515639,"about_ca_topic_score_gemma":0.0005960804,"domain_scores_codex":[0.9996467,0.0001036334,0.00003720275,0.00004971095,0.0001211564,0.00004162452],"domain_scores_gemma":[0.9994312,0.0001532276,0.0001661157,0.00006163626,0.0000839156,0.0001039355],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007109692,0.00001553423,0.00005999643,0.00004672558,0.000003249472,0.00003417513,0.0000101218,0.00002672144,0.9991263,0.00002302324,0.00001408117,0.0005691001],"study_design_scores_gemma":[0.000005363621,0.0002699847,0.0005068503,0.000004654634,0.000008235282,0.00007962267,0.000009752154,0.0001400817,0.9982828,0.00001634026,0.00067363,0.000002709502],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9879269,0.002491532,0.005838496,0.0002140679,0.0001314096,0.00008201627,0.0008611908,0.0001606835,0.002293707],"genre_scores_gemma":[0.98529,0.001309764,0.01036681,0.00004647961,0.00002587908,0.00004267572,0.0009714181,0.00003725876,0.001909855],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006773275,"threshold_uncertainty_score":0.002176046,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01227420977592395,"score_gpt":0.2521808789341722,"score_spread":0.2399066691582483,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}