{"id":"W2031560291","doi":"10.1002/art.38583","title":"A157: Macrophage Activation Syndrome‐like Illness Due to an Activating Mutation in NLRC4","year":2014,"lang":"en","type":"article","venue":"Arthritis & Rheumatology","topic":"Autoimmune and Inflammatory Disorders Research","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children; Alberta Children's Hospital","funders":"","keywords":"Immunology; Missense mutation; NLRC4; Macrophage activation syndrome; Innate immune system; Hemophagocytic lymphohistiocytosis; Biology; Exome sequencing; Inflammasome; Medicine; Mutation; Inflammation; Immune system; Genetics; Disease; Gene; Caspase 1; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002335746,0.001783194,0.0005828392,0.0005874825,0.0006720123,0.0004002555,0.0006068002,0.002188656,0.004477319],"category_scores_gemma":[0.0009728322,0.0002937913,0.0005767895,0.0003118127,0.0007212943,0.0003234445,0.000551626,0.0009615811,0.001382939],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004765039,"about_ca_system_score_gemma":0.0003019281,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004421127,"about_ca_topic_score_gemma":0.0003740362,"domain_scores_codex":[0.9998117,0.00002012435,0.00003175878,0.00005779334,0.00003655873,0.00004210413],"domain_scores_gemma":[0.9994335,0.0001837396,0.0001479187,0.00002314422,0.0000366292,0.0001751285],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"case_report","study_design_gemma":"case_report","study_design_scores_codex":[0.0005652569,0.0002375117,0.01920497,0.0001512792,0.00005177805,0.8971874,0.0002760123,0.0002105526,0.0779464,0.0004057031,0.0009781072,0.002785057],"study_design_scores_gemma":[0.0002479784,0.001597286,0.05572527,0.00005966439,0.0000794677,0.9229431,0.0002088817,0.0008802417,0.01483502,0.0003154739,0.003070903,0.00003668896],"study_design_candidate":"case_report","study_design_consensus":"case_report","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9956163,0.0005254984,0.0008091601,0.0004962188,0.0001157258,0.00006990772,0.0002938659,0.0000815511,0.001991667],"genre_scores_gemma":[0.9972698,0.0001522017,0.0007339375,0.0002072795,0.0001256072,0.00002114418,0.0002302727,0.00002519795,0.001234364],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004477319,"threshold_uncertainty_score":0.01497811,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009763455809303783,"score_gpt":0.2765334476428026,"score_spread":0.2667699918334989,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}