{"id":"W2031567251","doi":"10.1186/bcr2797","title":"Assessing interactions between the associations of common genetic susceptibility variants, reproductive history and body mass index with breast cancer risk in the breast cancer association consortium: a combined case-control study","year":2010,"lang":"en","type":"article","venue":"Breast Cancer Research","topic":"BRCA gene mutations in cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":97,"is_retracted":false,"has_abstract":true,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; Cancer Care Ontario; Mount Sinai Hospital","funders":"Division of Cancer Epidemiology and Genetics, National Cancer Institute; Medical Research and Materiel Command; Cancer Council Tasmania; National Health and Medical Research Council; Medical Research Council; Vaasan Keskussairaala; Universität Ulm; Cancer Council Victoria; Deutsche Krebshilfe; Robert Bosch Stiftung; Agency for Science, Technology and Research; Cancer Australia; Bundesministerium für Bildung und Forschung; National Breast Cancer Foundation; National Cancer Institute; Kuopion Yliopistollinen Sairaala; Breast Cancer Campaign; Lon V. Smith Foundation; Gentofte Hospital; National Institute for Health and Care Research; European Commission; National Institutes of Health; Deutsche Gesetzliche Unfallversicherung; Susan G. Komen for the Cure; Academy of Finland; Cancer Care Ontario; Deutsches Krebsforschungszentrum; Sundhed og Sygdom, Det Frie Forskningsråd; Cancer Research UK; Herlev Hospital; University of Minnesota; U.S. Department of Health and Human Services","keywords":"Breast cancer; Body mass index; Surgical oncology; Medicine; Case-control study; Ovarian cancer; Oncology; Family history; Gynecology; Cancer; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01820167,0.001485505,0.001969574,0.002503655,0.00148424,0.00221274,0.002233342,0.001751705,0.002456956],"category_scores_gemma":[0.02453751,0.001041395,0.00368673,0.003601388,0.0008728024,0.0007462651,0.001673916,0.001166829,0.0002792812],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006866683,"about_ca_system_score_gemma":0.001310657,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01031258,"about_ca_topic_score_gemma":0.0116882,"domain_scores_codex":[0.9791405,0.01063138,0.001862102,0.005014076,0.002627514,0.0007243981],"domain_scores_gemma":[0.978985,0.009384009,0.004866912,0.004151512,0.00163548,0.0009770819],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.002819157,0.0002193016,0.9759388,0.0001535042,0.01330594,0.0006034366,0.00019759,0.0004899796,0.002094154,0.0001405604,0.000387079,0.003650576],"study_design_scores_gemma":[0.0006162458,0.001204732,0.9794706,0.00005526049,0.01052156,0.001580583,0.0001753758,0.003733329,0.000762745,0.0003012321,0.001522934,0.0000554999],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9821272,0.003984131,0.01046598,0.0002023208,0.00009859672,0.0002451825,0.001947917,0.0001011103,0.0008275842],"genre_scores_gemma":[0.9916854,0.0004114704,0.004901222,0.0001082853,0.00008303955,0.0004627495,0.001796256,0.00004675641,0.0005049295],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01820167,"threshold_uncertainty_score":0.09626085,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03048025894468304,"score_gpt":0.3657763728397386,"score_spread":0.3352961138950555,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}