{"id":"W2031575390","doi":"10.3390/biom4040940","title":"Nuclear Transport of Yeast Proteasomes","year":2014,"lang":"en","type":"review","venue":"Biomolecules","topic":"Ubiquitin and proteasome pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canada Research Chairs; University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Karyopherin; Proteasome; Importin; Nuclear transport; Cytoplasm; Cell biology; Biology; Nucleus; Yeast; Ubiquitin; Cell nucleus; Saccharomyces cerevisiae; Chaperone (clinical); Nuclear localization sequence; Protein degradation; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001888351,0.000388945,0.0009599524,0.00009690603,0.00004124975,0.00001111425,0.0004576091,0.0004901068,0.00006158902],"category_scores_gemma":[0.00004086074,0.0003257764,0.0006670576,0.0001280098,0.0002150207,0.000001421878,0.00008955833,0.0001268071,0.0000805841],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000009132121,"about_ca_system_score_gemma":0.0001654314,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001241917,"about_ca_topic_score_gemma":0.000004561161,"domain_scores_codex":[0.9984498,0.00013853,0.0004960025,0.0004782978,0.0001723246,0.0002650471],"domain_scores_gemma":[0.9989023,0.000006778014,0.0003378626,0.0005923925,0.00005785446,0.0001028476],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00003033556,0.0001336121,0.000004858456,0.021596,0.0003677924,0.00001251054,0.00004062161,1.269546e-7,0.0142747,0.001050508,0.001365399,0.9611235],"study_design_scores_gemma":[0.0001330948,0.0002029113,0.000002181203,0.002096907,0.0001903622,0.00003683016,0.000006484215,3.431597e-7,0.008712742,0.0000135475,0.9882489,0.0003556614],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001666819,0.9960042,0.0001794156,0.000008187771,0.0001062401,0.0007299795,0.0002420639,0.00002490033,0.002538299],"genre_scores_gemma":[0.0008341448,0.9970769,0.0006012574,0.00003351134,0.0002902239,0.00008675053,0.0005418717,0.0001075795,0.0004277411],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9868835,"threshold_uncertainty_score":0.9999194,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02425580608250312,"score_gpt":0.289700079306421,"score_spread":0.2654442732239179,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}