{"id":"W2031625514","doi":"10.1097/01.jto.0000269737.05962.a0","title":"Weighing Tumor Biology in Treatment Decisions for Patients with Non-small Cell Lung Cancer","year":2007,"lang":"en","type":"review","venue":"Journal of Thoracic Oncology","topic":"Lung Cancer Treatments and Mutations","field":"Medicine","cited_by":40,"is_retracted":false,"has_abstract":false,"ca_institutions":"Princess Margaret Cancer Centre","funders":"","keywords":"Medicine; Lung cancer; Oncology; Epidermal growth factor receptor; Gemcitabine; Internal medicine; ERCC1; Targeted therapy; Cancer research; KRAS; Tyrosine kinase; Cancer; Predictive marker; Chemotherapy; Erlotinib; Adjuvant therapy; DNA repair; Gene; Biology; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003281059,0.000388496,0.002522235,0.0007608512,0.0000726842,0.00001090154,0.0001550062,0.0003311373,0.0000463883],"category_scores_gemma":[0.0000685062,0.0002156112,0.0005167131,0.0003108245,0.00004916596,0.0000547846,0.00002587662,0.0004126569,0.000003473087],"about_ca_system_candidate":true,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.003903497,"about_ca_system_score_gemma":0.004172471,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006601129,"about_ca_topic_score_gemma":0.0001925081,"domain_scores_codex":[0.9978801,0.0001172279,0.001154547,0.0002975044,0.0001432805,0.0004073099],"domain_scores_gemma":[0.9967998,0.0008978031,0.001476158,0.0002127139,0.0003868194,0.0002267387],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000655158,0.001570055,0.003995771,0.00190021,0.0009069502,0.0003040048,0.0002141625,0.00000559995,3.875069e-7,0.000003954788,0.0003192969,0.9901245],"study_design_scores_gemma":[0.004077719,0.00715621,0.0005277505,0.01082057,0.01081835,0.0001761933,0.00005583321,0.000006904577,0.000002911932,0.00001525318,0.9661451,0.0001972246],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.005566867,0.9887062,0.0008276704,0.0001258562,0.001228694,0.002536242,0.0001429494,0.000006716363,0.0008587591],"genre_scores_gemma":[0.0004986199,0.9833153,0.01449548,0.0001308706,0.0005679668,0.0003214242,0.0001202898,0.00006862692,0.0004814177],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9899272,"threshold_uncertainty_score":0.9999204,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05243648394124367,"score_gpt":0.5092956571945961,"score_spread":0.4568591732533525,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}