{"id":"W2031638626","doi":"10.4236/oji.2014.43012","title":"Memory Phenotypes of HIV-Specific CD8+ T Cell Responses Are Independent of Functional Activity as Defined by Cytokine Output","year":2014,"lang":"en","type":"article","venue":"Open Journal of Immunology","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Public Health Agency of Canada; University of Manitoba","funders":"Canadian Institutes of Health Research; Government of Canada; National Institutes of Health; Vaccine Research Center; National Institute of Allergy and Infectious Diseases; Manitoba Health Research Council","keywords":"Phenotype; CD8; C-C chemokine receptor type 7; Flow cytometry; Biology; Immunology; Cytotoxic T cell; Cytokine; Antigen; T cell; Cell biology; Immune system; In vitro; Genetics; Gene; Chemokine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0009258029,0.0002040871,0.000768302,0.000270512,0.0001272253,0.0000160406,0.0006870916,0.0002569162,0.001994958],"category_scores_gemma":[0.0002990047,0.0001593535,0.0001808095,0.000128815,0.00043926,0.0001843714,0.000306235,0.0005549911,0.0004382712],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008177206,"about_ca_system_score_gemma":0.0002966277,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001243696,"about_ca_topic_score_gemma":0.0000157801,"domain_scores_codex":[0.9976411,0.001020312,0.0006367413,0.0002243287,0.0001284537,0.0003490955],"domain_scores_gemma":[0.9974614,0.000670936,0.001027802,0.0003729166,0.0004211846,0.00004580911],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.01213895,0.001378487,0.002818709,0.00001817295,0.0008528,0.00002602702,0.0001619468,0.0000136589,0.9548435,0.0001902374,0.01298808,0.01456949],"study_design_scores_gemma":[0.008426757,0.003507113,0.06372776,0.00006864084,0.00007685357,0.0004423507,0.0004891983,4.104663e-7,0.8660437,0.0002449143,0.05680677,0.0001654681],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9872069,0.00696359,0.0004747361,0.0007332521,0.0005167204,0.0002272045,0.0001938325,0.00000564741,0.003678075],"genre_scores_gemma":[0.9926578,0.000555627,0.0001543515,0.000030496,0.0000271782,0.000007759167,0.00005520899,0.0000168449,0.006494748],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.08879967,"threshold_uncertainty_score":0.9989173,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02356596159512039,"score_gpt":0.2577672811406011,"score_spread":0.2342013195454807,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}