{"id":"W2031669769","doi":"10.4081/dts.2012.e8","title":"Preparation and preclinical evaluation of aceclofenac loaded pectinate mucoadhesive microspheres","year":2012,"lang":"en","type":"article","venue":"Drugs and Therapy Studies","topic":"Advanced Drug Delivery Systems","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Royal College of Physicians and Surgeons of Canada","funders":"","keywords":"Aceclofenac; Particle size; Mucoadhesion; Chemistry; Drug; Drug delivery; Microsphere; In vivo; Pharmacology; Dosage form; Polymer; Chromatography; Liberation; Biomedical engineering; Drug carrier; Materials science; Nanotechnology; In vitro; Chemical engineering; Medicine; Organic chemistry; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001650236,0.0001538404,0.0003005361,0.00003069516,0.000193393,0.000006319776,0.00004726166,0.0001212975,0.00005700245],"category_scores_gemma":[0.0001388457,0.0001234069,0.00003959464,0.00006902531,0.0002934044,0.0001869493,0.00005341544,0.00016157,0.000006778975],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002901442,"about_ca_system_score_gemma":0.00002002594,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000009923673,"about_ca_topic_score_gemma":0.000004027182,"domain_scores_codex":[0.9985312,0.0005843013,0.000309259,0.0002008035,0.0001604438,0.0002139507],"domain_scores_gemma":[0.9987477,0.000587025,0.0002099507,0.00009850468,0.0002845259,0.00007226519],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003092129,0.0009231038,0.1583897,0.0002758989,0.003220311,0.000001486593,0.1538314,0.0003995336,0.1528083,0.001653027,0.003715847,0.5216892],"study_design_scores_gemma":[0.01828301,0.001345568,0.06014731,0.0001531122,0.001280912,0.00004066881,0.0487279,0.005509801,0.6535228,0.005755811,0.2040665,0.001166562],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8597988,0.1383514,0.000009196993,0.0001846108,0.0005402684,0.0005374762,0.000009843486,0.00002293216,0.0005455088],"genre_scores_gemma":[0.983628,0.0155522,0.00008488195,0.0001886232,0.0001844833,0.00008558075,0.000003606935,0.00001064768,0.0002620235],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5205227,"threshold_uncertainty_score":0.5032386,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2802172540394174,"score_gpt":0.5436926248940775,"score_spread":0.2634753708546602,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}