{"id":"W2031669769","doi":"10.4081/dts.2012.e8","title":"Preparation and preclinical evaluation of aceclofenac loaded pectinate mucoadhesive microspheres","year":2012,"lang":"en","type":"article","venue":"Drugs and Therapy Studies","topic":"Advanced Drug Delivery Systems","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Royal College of Physicians and Surgeons of Canada","funders":"","keywords":"Aceclofenac; Particle size; Mucoadhesion; Chemistry; Drug; Drug delivery; Microsphere; In vivo; Pharmacology; Dosage form; Polymer; Chromatography; Liberation; Biomedical engineering; Drug carrier; Materials science; Nanotechnology; In vitro; Chemical engineering; Medicine; Organic chemistry; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006809407,0.0004371375,0.0005299415,0.0003245494,0.0001570861,0.0002639345,0.0003051275,0.0005576244,0.0008306974],"category_scores_gemma":[0.0002516341,0.0002192239,0.0005264821,0.0001970662,0.0002198936,0.0003799863,0.0001203469,0.0007165389,0.000284139],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002386473,"about_ca_system_score_gemma":0.0002958499,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005440247,"about_ca_topic_score_gemma":0.0007238404,"domain_scores_codex":[0.9997992,0.000032402,0.00001991893,0.00003225518,0.00006991727,0.00004633796],"domain_scores_gemma":[0.9998519,0.00001895496,0.00005532464,0.00001556076,0.00002966948,0.0000285358],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004936083,0.000567142,0.0001158087,0.0001038201,0.00002028783,0.00007137321,0.00002077495,0.0003382084,0.9923868,0.00007209041,0.0000734674,0.005736711],"study_design_scores_gemma":[0.0001598346,0.01757514,0.001976944,0.00001093557,0.00008971161,0.0002264963,0.00001936837,0.001145644,0.975947,0.00003744647,0.002799126,0.00001244778],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9814595,0.005719511,0.00971127,0.0001989239,0.0001403949,0.0004974987,0.0004983729,0.0001447054,0.001629823],"genre_scores_gemma":[0.9798401,0.004959058,0.01052901,0.0001165141,0.0000577141,0.0004731073,0.0007513937,0.00004582879,0.003227261],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008306974,"threshold_uncertainty_score":0.003601193,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2802172540394174,"score_gpt":0.5436926248940775,"score_spread":0.2634753708546602,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}