{"id":"W2031680195","doi":"10.1046/j.1523-1747.2000.00835.x","title":"In Vitro and In Vivo Expression of Interleukin-1α and Tumor Necrosis Factor-α mRNA in Pemphigus Vulgaris: Interleukin-1α and Tumor Necrosis Factor-α are Involved in Acantholysis","year":2000,"lang":"en","type":"article","venue":"Journal of Investigative Dermatology","topic":"Autoimmune Bullous Skin Diseases","field":"Medicine","cited_by":182,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; Sunnybrook Health Science Centre","funders":"","keywords":"Acantholysis; Tumor necrosis factor alpha; Pemphigus vulgaris; In vivo; Tumor necrosis factor α; Interleukin; Medicine; In vitro; Cytokine; Pathology; Necrosis; Immunology; Cancer research; Biology; Autoantibody; Antibody","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00027942,0.0004424068,0.0003115438,0.0006123413,0.0002872619,0.0004341516,0.0001608971,0.0004273653,0.001704591],"category_scores_gemma":[0.0004314489,0.0003487387,0.00038042,0.0002484728,0.0005043799,0.0004408569,0.0001700312,0.00107836,0.0004841551],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003164831,"about_ca_system_score_gemma":0.0001457359,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003744779,"about_ca_topic_score_gemma":0.0002822608,"domain_scores_codex":[0.9997674,0.000059986,0.00002127519,0.00003561225,0.00003432314,0.00008139436],"domain_scores_gemma":[0.9995215,0.0002058173,0.00006344799,0.00005509115,0.00003952552,0.0001146557],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005734698,0.00007465446,0.0002547849,0.00003421511,0.000004455218,0.000120533,0.00003024675,0.00002449359,0.9984472,0.00005351503,0.00001035217,0.0003720966],"study_design_scores_gemma":[0.0001089386,0.00131517,0.01521404,0.00001176651,0.00006321683,0.001194141,0.0001573554,0.0006658603,0.9802736,0.0001342361,0.0008553183,0.000006387858],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9956292,0.001641526,0.00151632,0.000056085,0.00004177569,0.00002761581,0.0001529643,0.00001876911,0.0009157542],"genre_scores_gemma":[0.99568,0.001059384,0.0008183656,0.00004089021,0.00005100676,0.00005320389,0.0004179291,0.00001155046,0.001867692],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001704591,"threshold_uncertainty_score":0.005702496,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01683516736916811,"score_gpt":0.2624012261582246,"score_spread":0.2455660587890565,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}