{"id":"W2031690857","doi":"10.1038/sj.onc.1210921","title":"Activation of Rac1 and the exchange factor Vav3 are involved in NPM-ALK signaling in anaplastic large cell lymphomas","year":2007,"lang":"en","type":"article","venue":"Oncogene","topic":"14-3-3 protein interactions","field":"Biochemistry, Genetics and Molecular Biology","cited_by":71,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Ligue Contre le Cancer; Institute of Cancer Research; Institut National de la Santé et de la Recherche Médicale; Institut National Du Cancer; Association pour la Recherche sur le Cancer","keywords":"Biology; RAC1; Cancer research; Signal transduction; Anaplastic large-cell lymphoma; Guanine nucleotide exchange factor; Carcinogenesis; Lymphoma; Immunology; Genetics; Cancer","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002011389,0.0003373562,0.0001793276,0.0005606562,0.0005886211,0.0007018971,0.00033659,0.0005020014,0.00123796],"category_scores_gemma":[0.0002245771,0.0002571322,0.000230508,0.0002072715,0.0003017969,0.0004324738,0.0002931248,0.0006929808,0.0004493626],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007830824,"about_ca_system_score_gemma":0.000265935,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006639754,"about_ca_topic_score_gemma":0.0009101298,"domain_scores_codex":[0.9998044,0.00004006109,0.0000119554,0.00002868571,0.00005409271,0.00006074943],"domain_scores_gemma":[0.9998953,0.00001623517,0.00002997743,0.00001307575,0.00001424895,0.00003117422],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004613079,0.00005079464,0.003519333,0.00003261408,0.00001786997,0.0006156269,0.00003054713,0.0002853908,0.9888253,0.001864053,0.0002525068,0.00404473],"study_design_scores_gemma":[0.00009516149,0.0001549681,0.07256525,0.00001291911,0.00007275912,0.004906489,0.0001498537,0.0089194,0.9002702,0.002720014,0.01011513,0.00001779578],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9933942,0.002474565,0.001571117,0.0002733638,0.00002205046,0.0000108115,0.0001242992,0.00007088155,0.002058748],"genre_scores_gemma":[0.9978657,0.0003638476,0.0004533011,0.00002531367,0.000009455672,0.000008230892,0.0001389989,0.000008868409,0.001126419],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00123796,"threshold_uncertainty_score":0.005681694,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01182922451052398,"score_gpt":0.25213790406652,"score_spread":0.240308679555996,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}