{"id":"W2031694624","doi":"10.1002/cam4.307","title":"Recurring <scp>DNA</scp> copy number gain at chromosome 9p13 plays a role in the activation of multiple candidate oncogenes in progressing oral premalignant lesions","year":2014,"lang":"en","type":"article","venue":"Cancer Medicine","topic":"Genomic variations and chromosomal abnormalities","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; Occupational Cancer Research Centre","funders":"Canadian Cancer Society Research Institute; Canadian Institutes of Health Research; Terry Fox Research Institute; Canadian HIV Trials Network, Canadian Institutes of Health Research; Fondation Pour l'Audition","keywords":"Carcinogenesis; Biology; Cancer; Fluorescence in situ hybridization; Gene; Chromosome; Cancer research; Gene silencing; Oncogene; Phenotype; DNA; Molecular biology; Genetics; Cell cycle","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003910058,0.0001338993,0.000210889,0.00004881158,0.00007719072,0.000007354809,0.0001578821,0.00009169117,0.00002802385],"category_scores_gemma":[0.0001835684,0.0000940099,0.00003161808,0.0001512336,0.0001001857,0.000008835167,0.00006602839,0.0000817758,0.000001489243],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000758685,"about_ca_system_score_gemma":0.00008921226,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001173173,"about_ca_topic_score_gemma":0.002118435,"domain_scores_codex":[0.9989585,0.0001310139,0.0003067767,0.000228255,0.0001432809,0.0002322323],"domain_scores_gemma":[0.9994513,0.00007217089,0.0001568624,0.0002255072,0.0000532893,0.0000409084],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004142829,0.000069284,0.3233545,0.00007848576,0.00002438722,0.000002545724,0.003899286,0.00074978,0.6690615,0.0001036906,0.0005517671,0.002063284],"study_design_scores_gemma":[0.002778074,0.0003082546,0.07281592,0.0008193692,0.00003798821,0.00002470826,0.003492656,0.001416269,0.898272,0.0001517662,0.0197364,0.000146601],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9977368,0.0007032998,0.0001096886,0.0002369037,0.00008803448,0.0002514716,0.00001981138,0.00000500962,0.0008489676],"genre_scores_gemma":[0.9988509,0.0001915864,0.000117728,0.0001731362,0.0002518633,0.0001258423,0.0001172336,0.00001466657,0.0001570401],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2505386,"threshold_uncertainty_score":0.3833613,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01502699978472725,"score_gpt":0.2733198072504727,"score_spread":0.2582928074657454,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}