{"id":"W2031694624","doi":"10.1002/cam4.307","title":"Recurring <scp>DNA</scp> copy number gain at chromosome 9p13 plays a role in the activation of multiple candidate oncogenes in progressing oral premalignant lesions","year":2014,"lang":"en","type":"article","venue":"Cancer Medicine","topic":"Genomic variations and chromosomal abnormalities","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; Occupational Cancer Research Centre","funders":"Canadian Cancer Society Research Institute; Canadian Institutes of Health Research; Terry Fox Research Institute; Canadian HIV Trials Network, Canadian Institutes of Health Research; Fondation Pour l'Audition","keywords":"Carcinogenesis; Biology; Cancer; Fluorescence in situ hybridization; Gene; Chromosome; Cancer research; Gene silencing; Oncogene; Phenotype; DNA; Molecular biology; Genetics; Cell cycle","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002277339,0.0002735169,0.0003092822,0.0004905512,0.000198461,0.00053228,0.0001590881,0.0002820795,0.001690227],"category_scores_gemma":[0.0003820884,0.0001787521,0.0002492173,0.0004779411,0.0002884931,0.0001848464,0.0003059621,0.0005171063,0.0004917504],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003316907,"about_ca_system_score_gemma":0.0002209156,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001173715,"about_ca_topic_score_gemma":0.001671161,"domain_scores_codex":[0.9997558,0.00001561939,0.00001949515,0.00007261116,0.00008767412,0.00004866689],"domain_scores_gemma":[0.9997042,0.00006711932,0.000109305,0.00003054985,0.00003650613,0.00005233453],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0001441698,0.00001715381,0.01174071,0.00003173863,0.00001113485,0.0003727752,0.00003053022,0.00009493784,0.9853146,0.00004553074,0.00004249221,0.002154172],"study_design_scores_gemma":[0.00001219518,0.0001936893,0.3285208,0.000009905705,0.00003797564,0.002107688,0.0001053876,0.001584488,0.6653655,0.000121663,0.001928883,0.00001186476],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9973188,0.0002411895,0.001272463,0.00004684504,0.000003856789,0.00001745995,0.0005727971,0.0000703332,0.0004563252],"genre_scores_gemma":[0.9969953,0.000192061,0.001302742,0.00002594366,0.000003361106,0.00001896642,0.0008042331,0.00001899278,0.0006383127],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001690227,"threshold_uncertainty_score":0.005654395,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01502699978472725,"score_gpt":0.2733198072504727,"score_spread":0.2582928074657454,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}