{"id":"W2031725294","doi":"10.1634/stemcells.2008-0033","title":"Reprogrammed Mouse Fibroblasts Differentiate into Cells of the Cardiovascular and Hematopoietic Lineages","year":2008,"lang":"en","type":"article","venue":"Stem Cells","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":239,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of General Medical Sciences; National Heart, Lung, and Blood Institute; National Institutes of Health; University of Toronto","keywords":"Biology; Embryoid body; Cell biology; Induced pluripotent stem cell; KLF4; Embryonic stem cell; Cellular differentiation; Stem cell; SOX2; Endothelial stem cell; Hemangioblast; Haematopoiesis; Progenitor cell; P19 cell; Cell type; Adult stem cell; Molecular biology; Cell; In vitro; Genetics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002155945,0.0007702858,0.0003493393,0.0005337595,0.0001105318,0.0002558769,0.0003738323,0.0004186785,0.002736419],"category_scores_gemma":[0.0001459909,0.0003083093,0.0004650492,0.0002395795,0.0002067291,0.0001908912,0.0002507204,0.0007489203,0.002445106],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001257962,"about_ca_system_score_gemma":0.0001639464,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001832268,"about_ca_topic_score_gemma":0.000427521,"domain_scores_codex":[0.9996413,0.0000385422,0.00005967547,0.00009381619,0.0001259826,0.00004070538],"domain_scores_gemma":[0.9998229,0.00003234241,0.00004764556,0.00004633176,0.00002358273,0.00002717446],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002117735,0.00001432882,0.0001680909,0.00002828508,0.000006809738,0.000120806,0.00002027558,0.00005460761,0.997435,0.0001329576,0.00007005806,0.001927639],"study_design_scores_gemma":[0.00001431381,0.0001311352,0.001932927,0.00001677223,0.00003089864,0.0006840387,0.00002215706,0.0008307369,0.9839817,0.00007745664,0.01227085,0.000007143208],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8876479,0.00396925,0.08231615,0.0002262217,0.0005096654,0.0005305773,0.00651004,0.001683757,0.01660644],"genre_scores_gemma":[0.9056477,0.005694883,0.05201976,0.000266498,0.00007983375,0.0005200054,0.007724246,0.0003622735,0.0276848],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002736419,"threshold_uncertainty_score":0.00915426,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01224334683980287,"score_gpt":0.2173579516306656,"score_spread":0.2051146047908627,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}