{"id":"W2031748320","doi":"10.1007/s13365-015-0320-8","title":"Rabies virus phosphoprotein interacts with mitochondrial Complex I and induces mitochondrial dysfunction and oxidative stress","year":2015,"lang":"en","type":"article","venue":"Journal of NeuroVirology","topic":"Rabies epidemiology and control","field":"Immunology and Microbiology","cited_by":75,"is_retracted":false,"has_abstract":false,"ca_institutions":"Health Sciences Centre; St. Boniface Hospital; Public Health Agency of Canada; University of Manitoba","funders":"Canadian Institutes of Health Research; Canadian Food Inspection Agency; Research Manitoba","keywords":"Phosphoprotein; Biology; Oxidative stress; Rabies virus; Mitochondrion; Reactive oxygen species; Molecular biology; Virus; Cell biology; Virology; Biochemistry; Phosphorylation","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002557035,0.0002382687,0.0006723781,0.0001780982,0.0001314469,0.00002231939,0.0001709894,0.0003321155,0.00007993452],"category_scores_gemma":[0.0006983067,0.0001682043,0.00005894855,0.00006822783,0.0007718476,0.0002853289,0.00008820326,0.0007918273,0.0000154535],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002182646,"about_ca_system_score_gemma":0.0000918036,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008150486,"about_ca_topic_score_gemma":0.00008273679,"domain_scores_codex":[0.9979665,0.0008551166,0.0005345394,0.0002820635,0.00005562395,0.0003061314],"domain_scores_gemma":[0.9983625,0.0005463057,0.0006588182,0.0001482416,0.0001941821,0.00008997831],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.01585482,0.0001378825,0.00239637,0.000008865397,0.000309158,0.0001034517,0.0007283373,0.00003870978,0.9730893,0.000238128,0.003358328,0.003736647],"study_design_scores_gemma":[0.09735125,0.08208696,0.255283,0.0003041491,0.001852262,0.03427231,0.006308109,0.0001844962,0.3715789,0.00688191,0.1418101,0.002086531],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9931297,0.001954604,0.0005820619,0.001741474,0.002202423,0.00021712,0.00001683146,0.00001596988,0.0001397814],"genre_scores_gemma":[0.9980493,0.0001541634,0.000378299,0.0008873939,0.0003289435,0.000009814654,0.00001079089,0.00001561465,0.0001656911],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6015104,"threshold_uncertainty_score":0.6859171,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02698103419674053,"score_gpt":0.2495372713202073,"score_spread":0.2225562371234668,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}